Association between celiac disease and Crohn's disease - a challenge to the coloproctologist

Abstract

Over the past few years, many studies on the association between celiac disease and inflammatory bowel disease have been reported. The genetic origin of this association has prompted research that searches for a common link for the concomitant manifestation of these pathologies. Clinical studies aim not only to demonstrate this relation, but also to establish the epidemiological frequencies among affected individuals and their relatives as compared to the general population. The similar clinical symptoms, difficulties, diagnoses, and therapeutics are still a challenge, since this association is unknown to most coloproctologists, thereby culminating in treatments and surgical procedures with no benefits for the patient.

The Association of Crohn’s Disease, Celiac Disease and Selective Ig A Deficiency

“…The association of CD and CeD may be explained by shared genetic predisposition, increased gut permeability to antigens observed in both diseases [7,9,10,14,15,20].…”

“…Concomitant occurrence of CeD and CD is rare and has been reported in several case reports and series [9][10][11][12][13][14][15].…”