Prognóstico tardio em jovens com coronariopatia estável: evolução em 10 anos após intervenção coronária percutânea

Bienert, Igor Ribeiro de Castro; Ribeiro, Expedito E.; Kajita, Luiz J.; Perin, Marco Antônio; Campos, Carlos Augusto Homem de Magalhães; Trentin, Fabio; Lemos, Pedro A.

doi:10.1590/s2179-83972012000200009

Cited by 3 publications

(1 citation statement)

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“…4 In Brazil, publications on PCI in young subjects are scarce. 5,6 Thus, the authors analyzed the in-hospital results of most recent PCIs from the Angiocardio registry in patients under 40 years, retrospectively assessing their profile and in-hospital clinical outcomes. The predictors of major cardiac and cerebrovascular events (MACCE) of the entire study population were also evaluated.…”

Section: Discussionmentioning

confidence: 99%

Intervenção Coronária Percutânea em Pacientes Jovens

Cantarelli¹,

Castello²,

Gonçalves³

et al. 2014

Rev. Bras. Cardiol. Invasiva

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Background: Cardiovascular disease has shown increasing occurrence rates among young people and data of percutaneous coronary intervention (PCI) in this group are scarce. Our objective was to perform a retrospective evaluation of the profile and in-hospital clinical outcomes of young patients in this PCI registry. Methods: From 2006 to 2012, 6,288 patients were consecutively submitted to PCI, of whom 151 were < 40 years of age (Group 1) and 6,127 were ≥ 40 years of age (Group 2). Logistic regression models were applied to identify the predictors of cardiac events and major adverse cardiac and cerebrovascular events (MACCE) in the study population. Results: In Group 1, there was a prevalence of smoking, myocardial infection as a clinical presentation, single vessel disease (left anterior descending artery as the culprit vessel), thrombotic lesions, and TIMI flow 0/1. The clinical success of PCI (96.0 % vs. 95.5 %; p = 0.89), and the occurrence of MACCE (3.3% vs. 3.3%; p = 0.82), death (0.0% vs. 1.0%; p = 0.39, stroke (0.0% vs. 0.1%; p > 0.99), myocardial infarction (3.3% vs. 2.3%; p = 0.41) or emergency revascularization (0.6% vs. 0.03%; p = 0.56) were similar between groups. In the multivariate analysis, age and presence of functional class Killip III and IV were the variables that best explained the occurrence of MACCE. Conclusions: Patients with age < 40 years represented a small fraction of the cases in this series and had a clinical and angiographic profile different from the older patients, suggesting the need to establish primary prevention measures earlier in individuals with the observed profile.

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Section: Discussionmentioning

confidence: 99%