Triagem auditiva neonatal em recém-nascidos de mães soropositivas para o HIV

Manfredi, A; Zuanetti, Patrícia Aparecida; Mishima, Fabíola; Guedes-Granzotti, Raphaela Barroso

doi:10.1590/s2179-64912011000400014

Cited by 11 publications

(7 citation statements)

References 18 publications

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“…In this study, there was a trend towards more hearing loss in newborns exposed to maternal HIV in-utero (11.1%) than newborns not exposed to maternal HIV (6.6%) but this did not reach significance (p=0.217). This confirms that hearing impairment in newborns starts soon after birth [24, 39]. A previous Brazilian hearing screening of infants born to HIV-seropositive mothers had reported a prevalence of 10% but found no association between HIV exposure during pregnancy and hearing loss [39].…”

Section: Discussionsupporting

confidence: 75%

“…This confirms that hearing impairment in newborns starts soon after birth [24, 39]. A previous Brazilian hearing screening of infants born to HIV-seropositive mothers had reported a prevalence of 10% but found no association between HIV exposure during pregnancy and hearing loss [39]. The difference between the report of this present study and Manfredi et al may be due to the different electrophysiological tools used in the two studies.…”

Section: Discussionsupporting

confidence: 62%

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Comparison of auditory brainstem response in HIV-1 exposed and unexposed newborns and correlation with the maternal viral load and CD4+ cell counts

Fasunla¹,

Ogunbosi

Odaibo

et al. 2014

Aids

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Objective The effects of maternal HIV infection and antiretroviral therapy on hearing of HIV-exposed newborns in sub-Saharan Africa have not been investigated. We determined the prevalence of sensorineural hearing loss among HIV-exposed newborns and the association between the hearing threshold and maternal & newborn parameters. Design A cohort audiometric study of newborns between October 2012 and April 2013. Settings Secondary and tertiary hospital based study. Participants Consecutive 126 HIV-exposed and 121 HIV-unexposed newborns. Intervention Hearing screening of the newborns were done with Auditory Brainstem Response and compared with maternal HAART, CD4 cell counts, RNA viral loads and newborn CD4 percent. Main outcome measure Hearing threshold levels of both groups were measured and analyzed. Results 11.1% of HIV-exposed and 6.6% of unexposed newborns had hearing impairment (p=0.2214). 6.4% of HIV-exposed and 2.5% HIV-unexposed newborns had hearing threshold >20dBHL (p = 0.1578). There was no significant association between the hearing thresholds of HIV-exposed newborns and maternal CD4 cell counts (p = 0.059) but there was with maternal viral load (p=0.034). There was significant difference between the hearing thresholds of HIV-exposed newborns with CD4 % of ≤25 and >25. This study showed significant difference in the hearing of the 119 HAART-exposed newborns and 7 unexposed newborns (p=0.002; RR=0.13 [0.05–0.32]). Conclusion There was a trend towards more hearing loss in HIV-exposed newborns. However, hearing thresholds increase with increasing mothers’ viral load. This background information supports the need for further studies on the role of in-utero exposure to HIV and HAART in newborn hearing loss.

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Section: Discussionsupporting

confidence: 75%

Section: Discussionsupporting

confidence: 62%

Comparison of auditory brainstem response in HIV-1 exposed and unexposed newborns and correlation with the maternal viral load and CD4+ cell counts

Fasunla¹,

Ogunbosi

Odaibo

et al. 2014

Aids

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“…No abnormalities were found in the transient evoked otoacoustic emissions in the sample, showing that all infants presented normal cochlear function at birth. These data corroborates with Hearing disorders in HIV a study done with 247 newborns, in which the study group consisted of 80 children that had a HIV seropositive mother, that also showed no association between HIV exposure, during pregnancy, and absence of otoacoustic emissions (14) .…”

Section: Discussionsupporting

confidence: 86%

Ocorrência de alterações auditivas em lactentes expostos à transmissão vertical do HIV

Padilha

Maruta

Azevedo

2018

Audiol., Commun. Res.

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RESUMO Objetivo Verificar a ocorrência de alterações auditivas periféricas e centrais em lactentes expostos à transmissão vertical do HIV. Métodos Análise retrospectiva de 144 prontuários de lactentes que passaram por avaliação auditiva ao nascimento, entre janeiro de 2010 e dezembro de 2015, com pesquisa das emissões otoacústicas evocadas por estímulo transiente e do potencial evocado auditivo de tronco encefálico. Os lactentes foram distribuídos em dois grupos: grupo estudo (GE), composto por 72 lactentes com mães soropositivas para o HIV e grupo controle (GC), com 72 lactentes sem risco para perda auditiva. O GE teve, ainda, os resultados do monitoramento auditivo aos 6 meses de idade analisados. Resultados Os grupos não se diferenciaram em relação à idade e ao gênero. Os resultados das emissões otoacústicas foram normais em ambos os grupos, revelando função coclear normal. Houve tendência do grupo estudo de apresentar maior ocorrência de alterações centrais no potencial evocado auditivo de tronco encefálico. A maioria dos lactentes não compareceu ao monitoramento auditivo e, entre os presentes, houve identificação de alteração audiológica. Conclusão Não houve alteração de função coclear na população estudada. Houve tendência de mais alterações centrais no grupo estudo, com predomínio das alterações de tronco baixo. Houve pouca adesão ao monitoramento auditivo e baixa concordância entre a primeira e a última avaliação.

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“…However, universal access to SUS users is not yet a reality in Brazil (3,4) . The current national index of universal screening is 37.5% (5) , representing an inferior benchmark than the one recommended and endorsed by the Multiprofessional Committee on Hearing Health (Comitê Multiprofissional em Saúde Auditiva -COMUSA) (6) and by the Joint Committee on Infant Hearing (7) .…”

Section: Introductionmentioning

confidence: 99%

Análise da cobertura da triagem auditiva neonatal no Nordeste brasileiro

Dias

Paschoal

Cavalcanti

2017

Audiol., Commun. Res.

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Introduction: Universal Neonatal Hearing Screening (UNHS) is the recommended screening test for hearing loss diagnosis. Purpose: To perform a spatial analysis of the coverage of the Neonatal Hearing Screening (NHS) in the Northeastern of Brazil and to verify the possible association of the coverage with the number of Speech-Language Pathology and Audiology (SLPA) maternities and reference centers in hearing health. Methods: The reference population was of live newborns registered in the Live Birth Information System (Sistema de Informação sobre Nascidos Vivos -SINASC). For the data collection, electronic banks were set up in the Health Information Systems. Exploratory spatial analysis was performed using TabWin software; Descriptive statistical analysis: absolute and relative distribution and weighted mean calculation; Analytical, using Chi-square and Fisher's Exact tests, in which a significance level of 0.05 was adopted. Results: There was similarity throughout the Northeastern, regarding the low coverage of the NHS. The highest indices were concentrated in specific areas and there was a homogenous distribution among states. However, the states of Piauí and Paraíba stand out as to the frequency of coverage in municipalities with the NHS service. It was found an association between the coverage and the number of maternities, Speech-Language Pathology and Audiology and centers of reference in hearing health. Conclusion:The low coverage of the triage prevails throughout the Northeastern, and the best coverages are found in peculiar areas, where the large population centers are located. There was association with the lack of Speech-Language Pathology and Audiology enrolled in the Unified Health System, centers of reference in hearing health and the number of maternities.

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Triagem auditiva neonatal em recém-nascidos de mães soropositivas para o HIV

Abstract: There was no association between the absence of TOAE and the newborn's HIV exposure during gestation.

Cited by 11 publications

References 18 publications

Comparison of auditory brainstem response in HIV-1 exposed and unexposed newborns and correlation with the maternal viral load and CD4+ cell counts

Comparison of auditory brainstem response in HIV-1 exposed and unexposed newborns and correlation with the maternal viral load and CD4+ cell counts

Ocorrência de alterações auditivas em lactentes expostos à transmissão vertical do HIV

Análise da cobertura da triagem auditiva neonatal no Nordeste brasileiro

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