2015
DOI: 10.1590/s1984-82502015000400016
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Abstract: Acetyl hexapeptide-3 has been used in anti-aging topical formulations aimed at improving skin appearance. However, few basic studies address its effects on epidermis and dermis, when vehiculated in topical formulations. Thus, the objective of this study was to determine the clinical efficacy of acetyl hexapeptide-3 using biophysical techniques. For this purpose, formulations with and without acetyl hexapeptide-3 were applied to the ventral forearm and the face area of forty female volunteers. Skin conditions w… Show more

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Cited by 16 publications
(14 citation statements)
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References 17 publications
(32 reference statements)
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“…Acetyl hexapeptide‐3 (G3 group) seems to contribute significantly to the retention of the TEWL. The significant decrease in TEWL after 40 days of treatment with the peptide may be associated with the observed increase in the moisturization of stratum corneum reported by Tadini et al …”
Section: Resultsmentioning
confidence: 99%
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“…Acetyl hexapeptide‐3 (G3 group) seems to contribute significantly to the retention of the TEWL. The significant decrease in TEWL after 40 days of treatment with the peptide may be associated with the observed increase in the moisturization of stratum corneum reported by Tadini et al …”
Section: Resultsmentioning
confidence: 99%
“…Furthermore, acetyl hexapeptide‐3 proved to be an effective ingredient due to its reduction in anisotropy of face skin and probable action on its mechanical properties …”
Section: Introductionmentioning
confidence: 99%
“…O acetilhexapeptídeo-3 apresentou um efeito significativo na diminuição da anisotropia da pele da região da face em comparação ao placebo; na região interna do antebraço, não foi verificada diferença significativa, quando comparado ao placebo. Em relação à hidratação, tanto na região da face como no antebraço, não houve resultados estatisticamente significativos (30).…”
Section: Rugas Profundasunclassified
“…Ao contrário da maioria dos trabalhos, Tadini e cols (2013) mostraram que a aplicação do acetilhexapeptídeo-3, na região interna do antebraço, não causou alteração significativa na pele, sugerindo que os efeitos das formulações cosméticas nas duas regiões estudadas são diferentes (30). Levando em consideração o fato de a pele da região da face, pescoço e colo é mais vulnerável ao fotoenvelhecimento do que a parte interna do antebraço, suas características são bastante diferentes.…”
Section: Rugas Profundasunclassified
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