2018
DOI: 10.1590/s1984-296120180071
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Abstract: This study aimed to evaluate the occurrence of nematode resistance to anthelmintics on sheep herds from the semi-arid region of Paraíba, Northeastern Brazil. Fecal Egg Count Reduction Test (FECRT) was carried out on 20 properties. In each herd, 30 animals were divided into five groups containing six animals each: group I, treated with albendazole 10%, 4 mg/kg; group II, ivermectin 0.08%, 0.2 mg/kg; group III, closantel 10%, 10 mg/kg; group IV, levamisole hydrochloride 5%, 5 mg/kg; and group V, monepantel 2.5%,… Show more

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Cited by 23 publications
(11 citation statements)
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References 27 publications
(31 reference statements)
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“…Bartley [15] emphasized that the anthelmintic resistance of GINs in small ruminants has been observed worldwide. Francisca Flávia da Silva [16] reported multi-resistance in all evaluated farms, wherein 95% of the farms showed high resistance to albendazole; 85%, ivermectin; 80%, closantel; 40%, levamisole; and 45%, monepantel. In another study involving 35 sheep farms in the state of São Paulo, resistance to albendazole and ivermectin was observed in 100% of the farms, whereas 92% showed resistance to closantel and 53% to levamisole [17].…”
Section: Discussionmentioning
confidence: 96%
“…Bartley [15] emphasized that the anthelmintic resistance of GINs in small ruminants has been observed worldwide. Francisca Flávia da Silva [16] reported multi-resistance in all evaluated farms, wherein 95% of the farms showed high resistance to albendazole; 85%, ivermectin; 80%, closantel; 40%, levamisole; and 45%, monepantel. In another study involving 35 sheep farms in the state of São Paulo, resistance to albendazole and ivermectin was observed in 100% of the farms, whereas 92% showed resistance to closantel and 53% to levamisole [17].…”
Section: Discussionmentioning
confidence: 96%
“…The anthelmintics most frequently used in the control of gastrointestinal nematodes in the Brazilian Northeast are benzimidazol, ivermectin and levamisole. The use of these drugs has promoted the selection of multiresistant nematode populations (Silva et al, 2018). The molecular characterization of H. contortus anthelmintic resistance isolated from experimental animals demonstrated that the population was resistant to benzimidazol and levamisole.…”
Section: Discussionmentioning
confidence: 99%
“…The control of these nematodes is performed with the administration of anthelmintics. However, the continuous use of these drugs has inevitably led to the development of resistant and/or multiresistant nematode populations worldwide (Kotze & Prichard, 2016;Santos et al, 2017), including in northeastern Brazil (Silva et al, 2018).…”
Section: Introductionmentioning
confidence: 99%
“…Bartley [15] emphasized that the anthelmintic resistance of gastrointestinal nematodes of small ruminants has been observed worldwide. Francisca Flávia da Silva [16] reported, multi resistance was observed in all evaluated farms, wherein 95% of farms had high resistance to albendazole, 85% to ivermectin, 80% to closantel, 40% to levamisole, and 45% to monepantel. In another study involving 35 sheep farms in the state of São Paulo, resistance to albendazole and ivermectin was observed in 100% of the farms studied, while 92% showed resistance to closantel and 53% to levamisole [17].…”
Section: Discussionmentioning
confidence: 92%