“…Moreover, bleeding in other sites may also occur, especially in the form of petechiae and suffusions in the skin, oral mucosa and nasal planum (FIGHERA et al, 2010). Anemia with the presence of anisocytosis, polychromasia and Howell-Jolly bodies was found in the CBC of dogs testing positive by PCR for piroplasmids in this study, and such findings are also reported in the literature (FIGHERA, 2007;FIGHERA et al, 2010;FRANÇA et al, 2010;LEMOS et al, 2017). Thrombocytopenia, another frequent finding among dogs positive for R. vitalii in this study, has also been reported in dogs with rangeliosis, in response to defects in platelet aggregation associated with impaired release of adenosine diphosphate (ADP) (PAIM et al, 2012;LEMOS et al, 2017).…”