2016
DOI: 10.1590/s1984-29612016008
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Abstract: Frequent and inappropriate use of all classes of antiparasitic drugs in small ruminants has led to failures in their effectiveness, culminating in a global problem of anthelmintic resistance. Brazil stands out as one of the world's leaders in publications about anthelmintic resistance, and for having the most numerous reports of this resistance in small ruminants in the Americas. These studies have involved mainly the fecal egg count reduction test (FECRT) and its correlation with field management practices. I… Show more

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Cited by 52 publications
(29 citation statements)
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“…In Brazil, the most commonly used anthelmintics belong to three families: benzimidazoles, imidozotiazoles, and macrocyclic lactones. However, none of these drugs are effective for treating ruminant animals infected with gastrointestinal nematodes, especially Haemonchus contortus (Salgado and Santos, 2016). Few studies have investigated anthelmintic resistance in gastrointestinal nematodes of cattle in northeastern Brazil.…”
Section: Introductionmentioning
confidence: 99%
“…In Brazil, the most commonly used anthelmintics belong to three families: benzimidazoles, imidozotiazoles, and macrocyclic lactones. However, none of these drugs are effective for treating ruminant animals infected with gastrointestinal nematodes, especially Haemonchus contortus (Salgado and Santos, 2016). Few studies have investigated anthelmintic resistance in gastrointestinal nematodes of cattle in northeastern Brazil.…”
Section: Introductionmentioning
confidence: 99%
“…Attempts to reduce losses have led to significantly increased frequency and doses applied in anthelmintic treatments, causing irreversible resistance of GIN to practically all the available active ingredients (SALGADO & SANTOS, 2016). Haemonchus contortus stands out among these parasites, mainly due to its hematophagous nature and high prolificacy of females (GETACHEW et al, 2007).…”
Section: Introductionmentioning
confidence: 99%
“…In livestock, parasitic diseases constitute one of the biggest barriers to animal production, directly affecting productivity and leading to high economic losses (GRISI et al, 2014). The increasing nematode resistance to commercially available drugs, in addition to the presence of residues from these drugs in the environment and in foods of animal origin (SALGADO & SANTOS, 2016), which may affect consumer health, has encouraged research to develop alternative methods for control. Based on this scenario, it remains an important challenge to find biologically active compounds that are effective and at the same time less harmful to the environment.…”
Section: Introductionmentioning
confidence: 99%