2014
DOI: 10.1590/s1984-29612014004
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Abstract: The objective of this study was to analyze morphological changes and parasite loads in the adrenal gland from 45 dogs with visceral leishmaniasis (VL). The animals were from the Zoonosis Control Center of Araçatuba, state of São Paulo, which is an endemic region for the disease. These animals were euthanized due to positive diagnoses of VL. The dogs were classified into asymptomatic, oligosymptomatic and symptomatic groups. The parasite load was determined by immunohistochemistry, using VL-positive dog hyperim… Show more

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Cited by 6 publications
(6 citation statements)
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References 29 publications
(31 reference statements)
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“…In such latter cases, increased troponin I has also been reported . Abnormal endocrine variables are rare, although amastigotes and inflammatory lesions have been found in the adrenal cortex of leishmaniotic dogs …”
Section: Laboratory Abnormalities That May Support or Confirm Leishmamentioning
confidence: 99%
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“…In such latter cases, increased troponin I has also been reported . Abnormal endocrine variables are rare, although amastigotes and inflammatory lesions have been found in the adrenal cortex of leishmaniotic dogs …”
Section: Laboratory Abnormalities That May Support or Confirm Leishmamentioning
confidence: 99%
“…27,57 Abnormal endocrine variables are rare, although amastigotes and inflammatory lesions have been found in the adrenal cortex of leishmaniotic dogs. 58,59 Assessment of renal function…”
Section: Biochemical Abnormalitiesmentioning
confidence: 99%
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“…The presence of vectorborne pathogens in the BM may induce substantial alterations in erythrocyte, granulocyte, monocyte, lymphocyte and thrombocyte numbers and/or function. Despite the high prevalence of CVBDs [6], only a few studies have investigated BM alterations in dogs infected solely by L. infantum [8][9][10] or by Ehrlichia canis [11]. In these studies, BM alterations associated with infections by L. infantum included emperipolesis, megakaryocytes dysplasia and BM aplasia, whereas myelosuppression was induced by E. canis infection.…”
Section: Introductionmentioning
confidence: 99%
“…The presence of vector-borne pathogens in the BM may induce substantial alterations in erythrocyte, granulocyte, monocyte, lymphocyte and thrombocyte numbers and/or function. Despite the high prevalence of CVBDs [ 6 ], only a few studies have investigated BM alterations in dogs infected solely by L. infantum [ 8 - 10 ] or by Ehrlichia canis [ 11 ]. In these studies, BM alterations associated with infections by L. infantum included emperipolesis, megakaryocytes dysplasia and BM aplasia, whereas myelosuppression was induced by E. canis infection.…”
Section: Introductionmentioning
confidence: 99%