Systematic review of dementia prevalence - 1994 to 2000

Abstract

Ageing has occurred in all regions of the world, with impact on neuropsychiatric disorders, particularly dementia. However, previous meta-analysis and reviews have shown high variability in world dementia prevalence rates.ObjectiveThe aim of this study was to perform a wide-ranging review of the dementia prevalence studies published in recent years.MethodsThe search was made on Medline, Lilacs and Embase databases for research conducted between 1994 and 2000. The main inclusion criteria were: use of standard diagnostic criteria and investigation of community samples.ResultsThe final selection included 42 papers, from all continents. The mean prevalence rate of dementia in subjects aged 65 years and older, for continents, ranged from 2.2% in Africa to 8.9% in Europe, and among countries, from 1.3% in India to 14.9% in Spain. However, there was a trend of clustering of the world prevalence rates with the majority of studies reporting rates between 4.2% and 7.2% (≥65 years). Age directly influenced the rates, with a mean prevalence rate of 1.2% (95% CI: 0.8.1.5) for the 65-69 years group and 39.9% (95% CI: 34.4.45.3) for the 90-94 year group, but showing less pronounced influence in the very elderly age group. The urban samples had higher rates, where no significant gender difference was evidenced.ConclusionThe age influence over dementia rates apparently leveled off in the very elderly group while a trend toward similar dementia prevalence rates around the world was probably influenced by greater homogeneity in diagnostic criteria.

Revisão sistemática sobre prevalência de demência entre a população brasileira

“…The prevalence rates found in the Brazilian studies have a wide interval between than (5.1% to 17.1%) and the mean prevalence of the Brazilian studies shows much higher prevalence rates than other regions of the world 27 , as the LAC rates, that can possibly be explained by sample characteristics (mean age, income, race etc.) and difference in the studies design and methods 28 . very different between the studies, but all show AD as the most frequent cause of dementia.…”

“…and difference in the studies design and methods 28 . very different between the studies, but all show AD as the most frequent cause of dementia. A great number of studies and reviews present AD with the most prevalent dementia subtype, despite of the variability of the rates worldwide [27][28][29] . Brazilian people trends to get higher prevalence of AD, like developed countries.…”

Comparative docking and ADMET study of some curcumin derivatives and herbal congeners targeting β-amyloid

“…MVD also determines volume of possible binding site before docking and cavity with largest volume is selected as docking point. Population of Indian subcontinent has very low risk of AD as compared to other continent of the world (Boersma et al 1998;Brayne et al 1998;Azzimondi et al 1998;Shaji et al 1996;Yamada et al 1999;Woo et al 1998;Lin et al 1998;Fillenbaum et al 1998;Herrera et al 1998;Lopes et al 2007). This may be due to regular consumption of curry spice turmeric and other herbal congeners by Indian population.…”

Prevalência de comprometimento cognitivo em adultos e idosos indígenas

“…A cada um ano de idade, a chance de comprometimento cognitivo aumentou em 3% e 9% nos participantes ≥ 50 anos, ≥ 60 anos e ≥ 65 anos, respectivamente. De fato, a idade é um fator de risco para o desenvolvimento de demência independente do país, e a prevalência dobra a cada 5 anos nos idosos com 65 anos ou mais (Jorm et al, 1987;Ferri et al, 2005;Lopes et al, 2007). Na população indígena, todos os estudos que analisaram os fatores associados ao risco para comprometimento cognitivo apontaram a idade como o principal fator de risco não modificável para o desenvolvimento do comprometimento cognitivo (Galasko et al, 2007;Brucki et al, 2014;Rodford et al, 2015;Lo Giudice et al, 2015).…”

“…Corroborando esse achado, um estudo brasileiro identificou que quanto menor o nível socioeconômico maior será a prevalência de demência em idosos não indígenas (Herrera et al, 2002;Lopes et al, 2007;Bottino et al, 2008;Fagundes et al, 2011). Em indígenas, muitos autores sustentam que as condições precárias de vida, com baixa renda familiar, moradias precárias, além acesso limitado a serviços de saúde constituem fatores relevantes no risco para o desenvolvimento de comprometimento cognitivo (Flicker et al, 2015).…”