Translation, cross-cultural adaptation and validation of SinoNasal Outcome Test (SNOT): 22 to Brazilian Portuguese

Abstract

Qual ity of life questionnaires have been increasingly used in clinical trials to help establish the impact of medical intervention or to assess the outcome of health care services. Among diseasespecific outcome measures, SNOT-22 was considered the most suitable tool for assessing chronic rhinosinusitis and patients with nasal polyps. Aims:To perform translation, cross-cultural adaptation and validation of the SNOT-22 to Brazilian Portuguese. Methods:Prospective study involving eighty-nine patients with chronic rhinosinusitis or nasal polyps submitted to functional endoscopic sinus surgery, who answered the questionnaire before and after surgery. Furthermore, 113 volunteers without sinonasal disease also answered the questionnaire. Internal consistency, test-retest reliability, measure validity, responsiveness and clinical interpretability were assessed.Results: Mean preoperative, postoperative and no sinonasal disease scores were 62.39, 23.09 and 11.42, respectively (p<0.0001); showing validity and responsiveness. Internal consistency was high (Cronbach's alpha = 0.9276). Reliability was sufficiently good, considering inter-interviewers (r=0.81) and intra-interviewers within a 10 to 14 day-interval (r=0.72). Surgery effect size was 1.55. Minimally important difference was 14 points; and scores up to 10 points were considered normal. Conclusion:The Brazilian Portuguese SNOT-22 version is a valid instrument to assess patients with chronic rhinosinusitis and nasal polyps. Braz J Otorhinolaryngol. 2011;77(5):663-9. ORIGINAL ARTICLE

Azithromycin for the Treatment of Eosinophilic Nasal Polyposis: Clinical and Histologic Analysis

“…The SNOT-22 index (difference between values from before and after the treatment) of the patients decreased, on average, 20.3 points. Nineteen patients (57.6%) exhibited a decrease of >14 points, which was considered significant 9 (Table 2). …”

“…The normality limit for the Brazilian SNOT-22 is 10 points, and a variation of >14 points among the SNOT-22 indexes of the same patient is considered significant. 9 The patients completed the SNOT-22 questionnaire before the beginning of the treatment and when they returned after 8 weeks of treatment.…”

Can we use the questionnaire SNOT-22 as a predictor for the indication of surgical treatment in chronic rhinosinusitis?

“…This means that the studied subjects may have had a better socioeconomic status than the patients of the studies of Kosugi et al 8 and Mascarenhas et al 13 whose subjects used a public health service.…”

“…Soler et al 8 conducted a study with 242 patients analysed over time and found that patients selected for the surgical treatment obtained worse SNOT-22 scores than patients who chose clinical treatment. Factors such as demographic characteristics, patient-doctor relationship, comorbidities and personality did not influence the surgical outcome.…”

Adaptasi Budaya, Alih Bahasa Indonesia, dan Validasi Sino-Nasal Outcome Test (SNOT)-22

“…Untuk menilai kondisi hidung pasien dilakukan dengan metode LundKennedy. 1,12 Analisis statistik dilakukan menggunakan SPSS 15.0 for windows. Pemakluman (informed consent) didapat dari semua partisipan yang masuk kriteria inklusi pada studi ini.…”