2011
DOI: 10.1590/s1807-59322011000600002
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Abstract: BACKGROUND:There are no reports on the long-term follow-up of patients with swine-origin influenza A virus infection that progressed to acute respiratory distress syndrome.METHODS:Four patients were prospectively followed up with pulmonary function tests and high-resolution computed tomography for six months after admission to an intensive care unit.RESULTS:Pulmonary function test results assessed two months after admission to the intensive care unit showed reduced forced vital capacity in all patients and low… Show more

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Cited by 42 publications
(40 citation statements)
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“…Data similar to this was presented by Quispe-Laime et al (12) in which 73% of the subjects had a BMI of ≥25kg/m², two of which For the identi ication of breathing disorders, presence of the restrictive pattern was veri ied in 5 out of the 11 evaluated patients, the exam was done around 40 (± 15.27) days after hospital discharge. Similar to our indings, Toufen et al (11) in his study followed-up 4 patients with Severe Acute Respiratory Syndrome (SARS) at the time of hospitalization for In luenza A (H1N1) who required invasive mechanical ventilation, two months after discharge a lung function exam was completed demonstrating a restrictive pattern in 3 patients and after 6 months the condition remained for 2 patients. Zarogoulidis et al (20) also discovered abnormal results in lung function immediately after discharge, he veri ied that FVC and FEV1 were reduced, after 3 months there was improvement which remained similar 6 months after discharge.…”
Section: Discussionsupporting
confidence: 79%
See 1 more Smart Citation
“…Data similar to this was presented by Quispe-Laime et al (12) in which 73% of the subjects had a BMI of ≥25kg/m², two of which For the identi ication of breathing disorders, presence of the restrictive pattern was veri ied in 5 out of the 11 evaluated patients, the exam was done around 40 (± 15.27) days after hospital discharge. Similar to our indings, Toufen et al (11) in his study followed-up 4 patients with Severe Acute Respiratory Syndrome (SARS) at the time of hospitalization for In luenza A (H1N1) who required invasive mechanical ventilation, two months after discharge a lung function exam was completed demonstrating a restrictive pattern in 3 patients and after 6 months the condition remained for 2 patients. Zarogoulidis et al (20) also discovered abnormal results in lung function immediately after discharge, he veri ied that FVC and FEV1 were reduced, after 3 months there was improvement which remained similar 6 months after discharge.…”
Section: Discussionsupporting
confidence: 79%
“…In the research conducted by Tougen Junior et al (11) patients were evaluated two and six months after ICU discharge, the pulmonary function exams showed reduced forced vital capacity (FVC) and a low carbon monoxide diffusion capacity. In another research which evaluated lung function and quality of life, no changes were perceived 6 months after hospital discharge (12).…”
Section: Introductionmentioning
confidence: 99%
“…However, much more extensive damage is caused in the mouse lung by H1N1 influenza viral infection (Kumar et al, 2011). Although there is clinical evidence for repair of the human lung after acute influenza infection (Toufen et al, 2011) precise mechanisms are still poorly understood. In the mouse it appears that a quite unexpected level of plasticity can be evoked in epithelial cells in response to signals expressed following such viral infection.…”
Section: Regional Epithelial Stem/progenitor Cell Populations Mediatimentioning
confidence: 99%
“…Toufen et al (33) evaluated patients with acute respiratory distress syndrome. The authors reported that, despite the marked severity of lung disease at admission, the patients in whom the acute respiratory distress syndrome was caused by infection with the swine-origin influenza A (H1N1) virus presented a late but substantial recovery over six months of follow-up.…”
Section: Exercisementioning
confidence: 99%