Comparison of Non-Invasive Methods for the Detection of Coronary Atherosclerosis

Bampi, Angela Bacelar Albuquerque; Rochitte, Carlos Eduardo; Favarato, Desidério; Lemos, Pedro A.; Luz, Protásio Lemos da

doi:10.1590/s1807-59322009000700012

Cited by 46 publications

(46 citation statements)

References 31 publications

(30 reference statements)

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“…Other studies have also shown that the triglyceride/HDL-c ratio is more predictive than the LDL-c level, including the Metabolic Syndrome in Active Subjects in Spain study, 23 the Boston Area Health Study, 24 the Women's Ischemia Syndrome Evaluation, 22 and the study by Bampi et al 10 Data from larger trials are also consistent with our findings. The Helsinki Heart Study showed that LDL-c was a poor predictor of myocardial risk, but that triglycerides and HDL-c were good predictors.…”

Section: Study Of the Use Of Lipid Panels As A Marker Of Insulin Resisupporting

confidence: 90%

“…9 In addition to being a good measure of insulin resistance, the ratio of triglycerides to HDL-c is a powerful predictor of CVD. [10][11][12][13] Yet insulin resistance, even when manifested by the metabolic syndrome, is often unrecognized in clinical practice. [14][15][16] The only American study that showed good recognition of the metabolic syndrome was based on a survey with only a 30% response rate.…”

Section: Introductionmentioning

confidence: 99%

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Study of the Use of Lipid Panels as a Marker of Insulin Resistance to Determine Cardiovascular Risk

Bertsch

2015

TPJ

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Section: Study Of the Use Of Lipid Panels As A Marker Of Insulin Resisupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Study of the Use of Lipid Panels as a Marker of Insulin Resistance to Determine Cardiovascular Risk

Bertsch

2015

TPJ

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“…Bampi et al observed that, Friesinger score 0-4 indicates less extensive disease and Friesinger score e"5 indicates extensive coronary atherosclerosis with extensive coronary artery disease. 25 In group I patients 56% had insignificant coronary artery disease and 44% had significant coronary artery disease defined by Friesinger index (n=100). In group II patients 6% had insignificant coronary artery disease & had 94% significant coronary artery disease.…”

Section: Discussionmentioning

confidence: 97%

“…[25][26][27] Female are less prone to developed IHD in premenopausal age due to protective role of estrogen, moreover smoking as a risk factor of IHD is less common in our country among female, which may explain male predominance of IHD. 28 The common risk factors for coronary artery disease in the present study showed that, smoking was the highest in Group-I followed by hypertension, family history of CAD, diabetes mellitus (DM) and dyslipidemia.…”

Section: Prolonged Qtc Dispersion and Leaman Scorementioning

confidence: 99%

Prolonged QTc Dispersion Correlates with Coronary Artery Disease in Acute ST Elevated Myocardial Infarction (STEMI)

et al. 2013

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Background: It has been found that there is strong association of QT dispersion and QT dispersion ratio with extent and severity of coronary artery disease. Qualitative importance of QTc dispersion on the base line ECG in patients with MI is recognized clinically but quantification of this phenomenon is less commonly used in clinical practice, which might be a better independent risk predictor of this group of patients. Methods: A total of 100 patients were selected, Study populations sub-divided into two groups on the basis of QTc dispersion. In group I (comparison group): QTc dispersion is <60 milliseconds (msec) in group II (study group) : QTc dispersion e60milliseconds(msec). 50 patients in each group. QT dispersion was calculated on standard resting 12 lead ECGs. QT interval was measured from the beginning of the inscription of the QRS complex to the point at which the T wave returned to the isoelectric line. Angiographic severity of coronary artery disease was assessed by- Vessel score, Friesinger score and Leaman score. Interpretation of coronary angiogram was reviewed by at least two cardiologists. . Results: The mean vessel score for group I patients was 1.16±0.68 and that of group II patients was 2.30±0.64 and the mean difference was statistically significant (p<0.05). Patients those had single vessel involvement had mean QTc dispersion 57.05, patients those had double vessel disease mean QTc dispersion was 102.00 and patients those had triple vessel involvement had mean QTc dispersion 177.60. There was a strong positive correlation with the QTc dispersion and increasing number of vessel involvement (Pearsons correlation coefficient). The mean Friesinger score for group I patients was 4.84±2.56 and that of group II patients was 9.80±2.60. The mean difference was significantly (p<0.05) higher in group II patients. There was a strong positive correlation between the QTc dispersion and Leaman score (Pearsons correlation coefficient). In group I patients 56% had insignificant coronary artery disease and 44% had significant coronary artery disease defined by Friesinger index (n=100). In group II patients 6% had Insignificant coronary artery disease & had 94% significant coronary artery disease. Conclusion: QTc dispersion>60 ms had independent predictive value for the severity of coronary artery disease. The greater the QTc dispersion the higher the number of coronary artery involvement. We observed that there is a positive correlation between prolonged QT dispersion and coronary artery disease severity in terms of Vessel score, Friesinger score, Leaman score. DOI: http://dx.doi.org/10.3329/cardio.v5i2.14322 Cardiovasc. j. 2013; 5(2): 173-181

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“…8,9,[21][22][23] These two lines represent the lumen-intima and media-adventitia interfaces. There is currently a slight disagreement regarding the location at which the measurements should be taken, but recommendations for carotid ultrasound scanning protocols 14,15 were published recently in order to improve the power of clinical studies.…”

Section: Discussionmentioning

confidence: 99%

Relation between intima-media thickness and bone mineral density in postmenopausal women: a cross-sectional study

et al. 2011

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Relation between intima-media thickness and bone mineral density in postmenopausal women: a cross-sectional study ABSTRACTCONTEXT AND OBJECTIVES: Controversy exists regarding the relationship between atherosclerosis and osteoporosis. The aim of this study was to determine the relationship between intima-media thickness (IMT) of the common carotid artery (CCA), presence of calcified atherosclerotic plaques and bone mineral density (BMD) evaluated by dual energy X-ray absorptiometry (DXA), in postmenopausal women. DESIGN AND SETTING:Cross-sectional study at Second Internal Medicine Clinic, Cluj-Napoca, Romania. METHODS:We studied the IMT (left and right CCA and mean IMT) and T-score (lumbar spine L2-L4, femoral neck and total hip) in 100 postmenopausal women (mean age 64.5 years). The presence of calcified atherosclerotic plaque and osteoporotic vertebral fractures was also noted. RESULTS:IMT in the left and right CCA and mean IMT were significantly associated with T-score measured for the lumbar spine L2-L4, femoral neck and total hip, with lower T-score, in the osteoporotic group than in the normal and osteopenic groups (P < 0.05). IMT had a significantly negative correlation with the lumbar spine T-score and femoral neck T-score; and mean IMT with lowest T-score. Mean IMT (P < 0.001), high blood pressure (P = 0.005) and osteoporotic vertebral fractures (P = 0.048) showed statistical significance regarding the likelihood of developing atherosclerotic plaque. CONCLUSIONS:In women referred for routine osteoporosis screening, the relationship between CCA, atherosclerosis and osteoporosis can be demonstrated using either cortical or trabecular BMD. Vertebral fractures may be considered to be a likelihood factor for atherosclerotic plaque development. RESUMÉN CONTEXTO Y OBJETIVOS:Hay controversias en cuanto a la relación entre la arterioesclerosis y la osteoporosis. El objetivo del estudio fue determinar la relación entre el espesor mío-intimal (EMI) de la arteria carótida común (ACC), la presencia de placas arterioescleróticas calcificadas, y la densidad mineral ósea (DMO) evaluada a través de absorciometría de rayos X de energía dual (DEXA) en mujeres posmenopáusicas. DISEÑO Y ENTORNO:Estudio transversal en la Segunda Clínica de Medicina Interna, Cluj-Napoca, Rumania. MÉTODOS:Hemos estudiado el EMI (ACC izquierda y derecha y EMI promedio) y el T-score (espina lumbar L2-L4, cuello femoral y cadera total) en 100 mujeres posmenopáusicas (edad promedia 64.5 años). Se ha observado también la presencia de las placas arterioescleróticas calcificadas y de la fractura vertebral osteoporótica.RESULTADOS: El EMI en ACC izquierda y derecha, como también el EMI promedio se ha asociado sobre todo con el T-score medido en la espina lumbar L2-L4, cuello femoral y cadera total o el valor más bajo del T-score, en el grupo osteoporótico, en comparación con el grupo normal y el osteopénico (P < 0.05). Se ha registrado una correlación significativamente negativa entre el EMI y el T-score de espina lumbar, el T-score del cuello femora...

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Comparison of Non-Invasive Methods for the Detection of Coronary Atherosclerosis

Cited by 46 publications

References 31 publications

Study of the Use of Lipid Panels as a Marker of Insulin Resistance to Determine Cardiovascular Risk

Study of the Use of Lipid Panels as a Marker of Insulin Resistance to Determine Cardiovascular Risk

Prolonged QTc Dispersion Correlates with Coronary Artery Disease in Acute ST Elevated Myocardial Infarction (STEMI)

Relation between intima-media thickness and bone mineral density in postmenopausal women: a cross-sectional study

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