2006
DOI: 10.1590/s1806-83242006000200015
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Abstract: ABSTRACT:The aim of this randomised, double blind controlled trial was to verify the efficacy of a herbal dentifrice on the reduction of plaque and gingivitis. Forty eight volunteers with established gingivitis were randomly assigned to either a test group (herbal dentifrice) or positive control group (dentifrice with triclosan and fluoride). The dentifrices were distributed in plain white tubes by an independent pharmacy, which revealed the contents of each tube only after the experimental period. Plaque and … Show more

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Cited by 69 publications
(69 citation statements)
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References 22 publications
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“…Previous studies also reported that an MTC dentifrice (20) and mouthwash (14) were clinically safe and reduced the plaque index and GBI after 21 and 15 days of use, respectively, which suggests that MTC has antimicrobial effects. In vitro studies showed that M. chamomilla was effective against 25 different gram-positive and gram-negative bacteria and 20 strains of Listeria monocytogenes (5).…”
Section: Discussionmentioning
confidence: 74%
“…Previous studies also reported that an MTC dentifrice (20) and mouthwash (14) were clinically safe and reduced the plaque index and GBI after 21 and 15 days of use, respectively, which suggests that MTC has antimicrobial effects. In vitro studies showed that M. chamomilla was effective against 25 different gram-positive and gram-negative bacteria and 20 strains of Listeria monocytogenes (5).…”
Section: Discussionmentioning
confidence: 74%
“…Among the 78 studies evaluated, 77 (98.72%) were classified as presenting a high risk of bias for all dimensions assessed; 6 (7.69%) for three dimensions; nine (11.54%) for two dimensions; and 27 (34.62%) for only one dimension. A single study (1.28%) 58 was classified as presenting low risk of bias for all of the dimensions. In summary, 77 (98.72%) of the articles were classified as studies presenting a high risk of bias and only one study (1.28%) was classified as presenting a low risk of bias.…”
Section: Resultsmentioning
confidence: 99%
“…For this dimension, among the 78 RCTs evaluated, 64 (82.05%) did not report on it or used an incorrect method, four studies (5.13%) were classified as unclear and only 10 studies (12.82%) used a method that was truly randomized for generating the allocation sequence for the groups. Among these ten randomized studies, five of them used simple or unrestricted randomization, among which four studies 24,39,44,58 used random number tables and one study 48 used a computer-generated random sequence. The other five authors used restricted sequences for generating the allocation: Botelho et al 17 used randomization in blocks, from a computer-generated list; Proano de Casalino and Guillen Galarza, 65 de Assis et al 32 and Peruzzo et al 63 tossed a coin; and Mora Loya et al 55 used a random number table, but in a restricted manner.…”
Section: Discussionmentioning
confidence: 99%
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“…[4] Herbal toothpaste is a unique formulation of natural ingredients that provide long lasting and complete oral care to gums and teeth .It contains herbal extract and essential oils that fights effectively against bacteria. The herbal paste not only cleans teeth but also bring freshness in breath [5], [6] . The use of herbal toothpaste is a good choice for everyone especially for them who are suffering from toothaches, bleeding gums and bad breathe.…”
Section: Chennaimentioning
confidence: 99%