2004
DOI: 10.1590/s1806-83242004000200006
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Abstract: ABSTRACT:The aim of the present parallel, double-blind investigation was to evaluate the effect of using systemic metronidazole alone or associated to scaling and root planing on adult chronic periodontal disease, monitored at baseline, 30, 60 and 90 days. Twelve subjects were divided into three groups: the first group (Group I -22 sites) was submitted to scaling and root planing (SRP) alone; the second group (Group II -30 sites) received SRP and 250 mg of metronidazole (3 times a day for 10 days), and the thi… Show more

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Cited by 10 publications
(7 citation statements)
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“…A statistically significant mean difference of 0.28 mm AE 0.09 and heterogeneity I 2 = 69%, in favour of the use of a systemic antibiotic was observed. AZI (0.39 mm AE 0.27, six studies, 185 patients, I 2 = 74%), CLA (0.88 mm AE 0.23, one study, 37 patients, AMOX + CLAV, DOXH and MET did not show a statistically significant mean difference when compared to the control group. At 9 mo, 164 patients out of five studies could be analysed.…”
Section: Probing Pocket Depth Reductionmentioning
confidence: 80%
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“…A statistically significant mean difference of 0.28 mm AE 0.09 and heterogeneity I 2 = 69%, in favour of the use of a systemic antibiotic was observed. AZI (0.39 mm AE 0.27, six studies, 185 patients, I 2 = 74%), CLA (0.88 mm AE 0.23, one study, 37 patients, AMOX + CLAV, DOXH and MET did not show a statistically significant mean difference when compared to the control group. At 9 mo, 164 patients out of five studies could be analysed.…”
Section: Probing Pocket Depth Reductionmentioning
confidence: 80%
“…Analysis of the abstracts resulted in 95 potential articles. In the third phase, the full text articles of the remaining 95 articles were evaluated, of which 40 did not pass the inclusion criteria (Table ). Another 12 articles were excluded because they were about patients with aggressive periodontitis.…”
Section: Resultsmentioning
confidence: 99%
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“…3,12 The BANA Test has been used in several studies. [13][14][15][16][17] The results of the BANA Test have been previously compared with other microbiological techniques, such as ELISA (enzyme-linked immunoabsorbent assay) reaction 18 and PCR. 19 However, these studies compared only the bacterial enzymatic activity with the presence or absence of the microorganisms.…”
Section: Introductionmentioning
confidence: 99%
“…Research over the last few years has shown that periodontal conditions have a negative impact on the quality of life related to oral health and patient life, including impairment, functional limitations, discomfort and disability [1]. This disease is influenced by several factors, the main factor in the progression of the illness is the bacterial plaque [19]. The bacteria adhere to the teeth surface and a biofilm is slowly formed.…”
mentioning
confidence: 99%