Correlação entre parâmetros clínicos e qualidade de vida relacionada à saúde em mulheres com DPOC

Abstract

Objective: To correlate health-related quality of life (HRQL) of women with COPD with clinical parameters and with the six-minute walk distance (6MWD; six-minute walk test). Methods: Cross-sectional study involving 30 female patients diagnosed with mild or moderate COPD treated at the Respiratory Outpatient Clinic of the Presidente Dutra University Hospital. Patients completed the Saint George's Respiratory Questionnaire (SGRQ) and were evaluated in terms of respiratory pressures, spirometry parameters and 6MWD. Descriptive statistical analysis was carried out, as were Student's t-tests for dependent variables, together with Pearson's and Spearman's correlation coefficients for numerical and ordinal variables, respectively. Results: According to the SGRQ total scores, HRQL was impaired, to some extent, in most of the participants. Most SGRQ total scores were between the second and the third quartiles, reflecting poor HRQL. The participants also presented poor functional capacity. Mean 6MWD (317.7 m), inspiratory muscle strength (−53.48 cmH 2 O) and expiratory muscle strength (69.5 cmH 2 O) were all below reference values. We found that HRQL was not correlated with body mass index or pulmonary function. However, HRQL presented a negative linear correlation with age, MIP and 6MWD, as well as a positive correlation with the sensation of dyspnea and fatigue. Conclusions: In this study, HRQL, determined using the SGRQ, was severely impaired in COPD patients, who presented severe limitations in functional capacity, breath control and personal life.Keywords: Quality of life; Pulmonary disease, chronic obstructive; Women. ResumoObjetivo: Correlacionar a qualidade de vida relacionada à saúde (QVRS) de mulheres portadoras de DPOC com parâmetros clínicos e com a distância percorrida no teste de caminhada de seis minutos (TC6). Métodos: Estudo transversal com 30 mulheres portadoras de DPOC leve ou moderada, atendidas no Ambulatório de Pneumologia do Hospital Universitário Presidente Dutra. Foi aplicado o Saint George's Respiratory Questionnaire (SGRQ), assim como foram realizadas as medidas das pressões respiratórias, da espirometria e dos resultados do TC6. Executou-se a análise estatística descritiva, assim como o teste t de Student para variáveis dependentes, o coeficiente linear de Pearson para correlações de variáveis numéricas e o de Spearman para variáveis ordinais. Resultados: A QVRS esteve, na grande maioria das mulheres entrevistadas, comprometida, em graus variados, de acordo com o escore total do SGRQ. Os escores totais do SGRQ da maioria das participantes estavam entre o segundo e o terceiro quartil, o que reflete baixa QVRS. As participantes apresentaram ainda baixa capacidade funcional no TC6, com distância média percorrida (317,7 m) e força muscular inspiratória (−53,48 cmH 2 O) e expiratória (69,5 cmH 2 O) abaixo dos valores de normalidade. Não houve correlação entre a QVRS e o índice de massa corpórea e a função pulmonar. No entanto, houve correlação linear negativa com a idade, a PImáx e o TC6 e c...

An official systematic review of the European Respiratory Society/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease

“…23 studies related to subjective fatigue were retrieved in full text and 12 were included in this section, all related to COPD [148][149][150][151][152][153][154][155][156][157][158][159].…”

“…Dimensions of subjective fatigue have been related to pulmonary function, skeletal muscle force and quality of life in COPD patients [154,155]. Subjective fatigue measured during the 6MWT using the Borg exertion scale is associated with lower 6MWT, slower gait speed, more severe lung disease, more dyspnoea on exertion and lower HRQoL (table S27) [148,[156][157][158]. Although there are fewer SAOUTI [131] LEE [135] PACIOCCO [130] MIYAMOTO [43] BENZA [133] NICKEL [136] TUPPIN [140] data available to assess the impact of subjective fatigue during 6MWT compared with dyspnoea, existing studies support its role as an important contributor to 6MWD and disease status in COPD.…”

O índice BODE correlaciona-se com a qualidade de vida em pacientes com DPOC?

“…(6) Studies of health-related quality of life (HRQoL) in patients with COPD with varying degrees of severity have consistently shown that these patients have significant decrements in HRQoL. (7,8) Therefore, HRQoL is an important clinical outcome in COPD.…”

Correlation between functional capacity and health-related quality of life in COPD: a case series

“…According to these authors, this may indicate that patients with better scores the walk test have their activities less restricted and experience less impact of the disease on their daily lives. Mangueira et al (29) also found a negative correlation (r = -0.3677) between the distance covered in the 6-MWT and the "total" SGRQ score in women with COPD. Dourado et al (30) also found a negative correlation with the domains of "Activities" (r = -0.58) and "Impacts" (r = -0.63).…”