Avaliação da qualidade de vida em pacientes submetidos a ressecção pulmonar por neoplasia

Abstract

Objective: To evaluate the health-related quality of life of patients submitted to resection of the pulmonary parenchyma due to neoplasia. Methods: The Medical Outcomes Study 36-item Short-Form Health Survey was used to evaluate patients in the preoperative period and on postoperative days 30, 90 and 180. We used the GEE statistical model, in which the dependent variable (quality of life) changes for each patient over the course of the evaluation. Independent variables were gender, age, educational level, type of surgery, radiotherapy, chemotherapy, forced vital capacity and 6-minute walk test. The level of significance adopted was 5%. Results: The final study sample comprised 36 patients, 20 of whom were men. Of those 36 patients, 17 were submitted to lobectomy, 10 to pneumonectomy, 6 to segmentectomy, and 3 to bilobectomy. Chemotherapy was used in 15 patients, radiotherapy in 2, and a combination of radiotherapy and chemotherapy in 2. Improved quality of life was seen in the following domains: social (on postoperative day 90); physical/functional (some patients presenting better forced vital capacity and 6-minute walk test performance); and physical (in patients undergoing smaller resections). Lowered quality of life was seen in the following domains: social (for female patients); physical/social (resulting from radiotherapy, chemotherapy or both); and physical/functional (by postoperative day 30). Conclusions: It is important that studies evaluating the various determinants of quality of life, as well as the impact that cancer treatment modalities have on such variables, be conducted. The knowledge provided by such studies can contribute to improving the quality of life of patients undergoing pulmonary resection due to neoplasia.

Quality of life of patients with lung cancer: A scoping review

“…A cross-sectional design was adopted in 55.6% (n=10) of the studies. Non-controlled prospective, "before and after" studies assessed QoL before and after chemotherapy 9,14 , before three cycles of chemotherapy 26 , before and after lung resectioning 21,22 , before and after physiotherapy 20 , before starting treatment and two and four months after the first evaluation and/or the beginning of treatment 27 .…”

“…The evaluation of QoL after physical therapy was described in one study, with improvement in physical mobility, pain, energy, emotional aspects and sleep 20 . The results after pulmonary resection are contradictory 21,22 , with both deterioration 21 and improvement in QoL 22 . Studies comparing the QoL of people with cancer with healthy individuals 5,18 found a worse overall QoL score for cancer patients in the SF-365 and WHOQoL-BREF 18 .…”

“…A study by Saad, Botega and Toro 22 evaluated QoL before surgery and 30, 90 and 180 days later. In the prospective cohort study by Lima et al 21 , QoL was evaluated only six months after pulmonary resection.…”

Avaliação da qualidade de vida e função pulmonar em pacientes com câncer de pulmão

“…O cálculo do tamanho da amostra foi realizado no programa Programs for Epidemiologists (PEPI) versão 4.0 e baseado no estudo de Saad et al 12 . Para um nível de significância de 5%, um poder de 90% e um tamanho de efeito de no mínimo 0,75 desvio Os pacientes foram divididos em dois grupos para as análises: grupo cirúrgico (GC) e grupo não cirúrgico (GNC).…”

Aplicação associada do questionario SF 36, CRQ e indices espirometricos em mulheres asmaticas

“…Entretanto não foi relatada influência da medicação em uso ao domínio em questão. Saad et al (2006) avaliaram através do SF 36 a qualidade de vida de pacientes com neoplasia pulmonar submetidos a ressecção de parênquima pulmonar. Avaliou-se o período pré-operatório, bem como o pós-operatório de 1, 3 e 6 meses de pacientes acompanhados por um programa de reabilitação pulmonar e observaram melhora da qualidade de vida na capacidade funcional nos pacientes com melhor desempenho no teste de caminhada de seis minutos e na CVF; aspectos físicos e estado geral de saúde nos pacientes com melhor desempenho no teste de caminhada de seis minutos; aspectos físicos nos pacientes com menor ressecção cirúrgica; aspectos sociais após três meses da cirurgia.…”