Tendência temporal e distribuição espacial da sífilis gestacional e congênita em Goiás, 2007-2017: um estudo ecológico

Nunes, Patrícia Silva; Guimarães, Rafael Alves; Rosado, Luiza; Marinho, Tamíris Augusto; Aquino, Érika Carvalho de; Turchi, Marília Dalva

doi:10.1590/s1679-49742021000100002

Cited by 6 publications

(3 citation statements)

References 13 publications

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“…However, efforts have not been sufficient to control the disease and research addressing the issue needs to be continued. In Brazil, the Stork Network ( 41 ), the implementation of rapid tests ( 42 ), the compulsory notification of congenital syphilis ( 43 ), the agenda of strategic actions to reduction of syphilis ( 44 ) and the No Syphilis Project ( 45 ) are governmental measures instituted that strengthen the maternal and child area, which contribute in terms of increasing the detection and notification of the disease, but it has also not been sufficient to eliminate congenital syphilis in the country.…”

Section: Discussionmentioning

confidence: 99%

Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study

et al. 2023

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ObjectiveThe study aimed to analyze the temporal trend of congenital syphilis in Brazil in the period from 2008 to 2018 and its spatial distribution in the Immediate Regions of Urban Articulation, and to identify spatial correlations with socioeconomic factors and prenatal care.MethodsSpatial correlations between the incidence of congenital syphilis and socioeconomic conditions and access to prenatal care were assessed. This ecological study conducted a time series analysis in Brazil and spatial analysis in 482 Immediate Regions of Urban Articulation. Cases of congenital syphilis reported in the Notifiable Diseases Information System and the Live Birth Information System from January 1, 2008, to December 31, 2018 were included. Socioeconomic conditions (percentage of individuals with inadequate water supply and sanitation) were extracted from the 2010 census, whereas the Live Birth Information System provided data on access to prenatal care (percentage of live births with 1–3 prenatal care appointments). The Joinpoint Regression software performed the temporal trend analysis, while the GeoDa software assessed territorial clusters using the Moran’s I and Local Spatial Association Indicator.ResultsThe incidence of congenital syphilis showed an upward trend (annual percent change 1 = 26.96; 95% CI: 18.2–36.3; annual percent change 2 = 10.25; 95% CI: 2.7–28.4) and was unevenly distributed across Immediate Regions of Urban Articulation in Brazil (Moran’s I = 0.264, p ≤ 0.05). It also presented a direct spatial correlation with the percentage of individuals with inadequate water supply and sanitation (Moran’s I = 0.02, p ≤ 0.05) and the percentage of live births with 1–3 prenatal care appointments (Moran’s I = 0.03, p ≤ 0.05).ConclusionAgrowth trend of congenital syphilis in Brazil was observed between 2008 and 2018. Moreover, inequalities in socioeconomic conditions and access to prenatal care influenced the spatial distribution of this disease.

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Section: Discussionmentioning

confidence: 99%

Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study

et al. 2023

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“…3 Increases in the number of CS cases have been reported in Brazil, at national level 2,4,16 or in local studies. 9,11,[17][18][19][20][21][22][23][24] In the country, the incidence of CS increased from 2.1 in 2009 to 8.2 per 1,000 LB in 2019, 2 but was supplanted fivefold by that of São Gonçalo.…”

Section: Discussionmentioning

confidence: 99%

“…The temporal analysis of CS in São Gonçalo shows an annual increase of 64.9% between 2010 and 2013 and 24.9% between 2013 and 2018, confirming the upward trend of other regions of Brazil, 11,16,17,[20][21][22][23][24] but with even greater intensity. Of these studies, those that estimated the APV in similar time periods described smaller increases: in Niterói, from 2007 to 2016, the APV was 16%; 11 in Pará, from 2007 to 2017, 12.3%; 17 in Goiás, from 2007 to 2017, 16.8%; 18 and in the Northeast, from 2008 to 2015, it was 19.9%. 20 Only three explored the trend according to sociodemographic variables.…”

Section: Discussionmentioning

confidence: 99%

Temporal trend of congenital syphilis in the most populous municipality of metropolitan region II of Rio de Janeiro state

Morais¹,

Pimentel²,

Kawa³

et al. 2023

Rev. paul. pediatr.

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This study aimed to explore the temporal trend in congenital syphilis, according to sociodemographic and prenatal care in the city of São Gonçalo -Rio de Janeiro, from 2007 to 2018.Methods: Ecological time series study, with data from SINAN (Information System for Notifiable Diseases) and SINASC (Information System on Live Births databases). We calculated annual incidence (per 1,000 live births) according to sociodemographic and prenatal variables. For the same variables, we calculated trends by logarithmic regression (Joinpoint Regression), estimating the annual percentage change.

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Spatiotemporal distribution analysis of syphilis in Brazil: Cases of congenital and syphilis in pregnant women from 2001–2017

Silva

Leony²,

Souza³

et al. 2022

PLoS ONE

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In Brazil, the notification of congenital (CS) and syphilis in pregnant women (SiP) is compulsory. Notification data provided by the Ministry of Health in combination with the mapping of vulnerable geographic areas is essential to forecasting possible outbreaks and more effectively combating infection through monitoring. We aim to evaluate the spatiotemporal distribution and epidemiological aspects of reported cases of CS and SiP in Brazil. A retrospective ecological study was carried out using secondary surveillance data obtained from the Brazilian National Notifiable Diseases Information System (SINAN) database, considering all reported cases of CS and SiP between 2001 to 2017. Epidemiological characteristics and time trends were analyzed using joinpoint regression models and spatial distribution, considering microregions or states/macroregions as units of analysis. A total of 188,630 (359/100,000 birth lives) CS and 235,895 of SiP (6.3/100,000 inhabitants) were reported during the period studied. In general, the epidemiologic profile of Brazil indicates most reported CS cases occurred in "mixed-race" newborns who were diagnosed within seven days of birth and whose mothers had received prenatal care, but the epidemiologic profile varies by Brazilian macroregion. Regarding SiP, most cases were among women who self-reported ‘mixed-race’, were aged 20–39 years, had up to eight years of formal education and were diagnosed with primary or latent syphilis. Approximately 549 (98.4%) and 558 (100%) microregions reported at least one case of CS and SiP, respectively. From 2012 to 2016, CS cases increased significantly in almost all Brazilian states, most notably in the South, Southeast, and Central-West macroregions, from 2001–2017 and the relative risk (RR) of SiP increased around 400% (RR: 1,00 to 445,50). Considering the epidemiological scenario of the infection in Brazil, it is necessary to enhance preventive, control and eradication measures.

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Tendência temporal e distribuição espacial da sífilis gestacional e congênita em Goiás, 2007-2017: um estudo ecológico

Cited by 6 publications

References 13 publications

Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study

Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study

Temporal trend of congenital syphilis in the most populous municipality of metropolitan region II of Rio de Janeiro state

Spatiotemporal distribution analysis of syphilis in Brazil: Cases of congenital and syphilis in pregnant women from 2001–2017

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