Introduction: Hypodermoclisis is a subcutaneous puncture technique that allows the infusion of fluids and drugs, is an ancient technique that has been replaced by new methods, currently being discussed with a view to recovering its practice, and to explore its peculiarities, allowing its implementation in the face of its benefits. Objective: To elaborate an illustrated puncture protocol in a public hospital in the interior of São Paulo. Method: This is a qualitative, exploratory and descriptive research, in order to obtain the images of the technique and its respective puncture sites, in order to develop an illustrated protocol. It was performed in the palliative care sector, with randomly selected patients, not considering their respective diagnoses and / or time of hospitalization. Result: Development of the illustrated protocol describing the materials used, and the technique for puncturing. Among the possible illustrated places are the regions: interscapular; subclavicular; deltoid; abdominal and anterolateral aspects of the thigh. Conclusion: It was possible to develop a facilitating and enlightening tool in the accomplishment of the hypodermoclisis technique, in a safe and objective way, providing a global view of this nursing assistance, being possible to align its execution form, visually and didactic