Fatores associados ao uso excessivo de medicação sintomática em pacientes com enxaqueca crônica

Guendler, Vera Z.; Mercante, Juliane Prieto Peres; Ribeiro, Reinaldo Teixeira; Zukerman, Eliova; Peres, Mário Fernando Prieto

doi:10.1590/s1679-45082012000300010

Cited by 2 publications

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“…Moreover, caffeine overuse is one of the risk factors of migraine chronification, thus promoting the transformation of episodic migraine into its chronic form (when headaches persist for ≥15 days/month for >3 months) [ 61 , 62 ]. It is important to note that caffeine consumption was not significantly connected to medication overuse in chronic migraine patients [ 63 ]. A question arises: What is the exact mechanism by which caffeine can induce migraine headache?…”

Section: Introductionmentioning

confidence: 99%

The Ambiguous Role of Caffeine in Migraine Headache: From Trigger to Treatment

2020

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Migraine is a chronic disorder, and caffeine has been linked with migraine for many years, on the one hand as a trigger, and on the other hand as a cure. As most of the population, including migraineurs, consume a considerable amount of caffeine daily, a question arises as to whether it influences their headaches. Indeed, drinking coffee before a migraine attack may not be a real headache trigger, but a consequence of premonitory symptoms, including yawning, diminished energy levels, and sleepiness that may herald a headache. Here, we aim to summarize the available evidence on the relationship between caffeine and migraines. Articles concerning this topic published up to June 2020 were retrieved by searching clinical databases, and all types of studies were included. We identified 21 studies investigating the prevalence of caffeine/caffeine withdrawal as a migraine trigger and 7 studies evaluating caffeine in acute migraine treatment. Among them, in 17 studies, caffeine/caffeine withdrawal was found to be a migraine trigger in a small percentage of participants (ranging from 2% to 30%), while all treatment studies found caffeine to be safe and effective in acute migraine treatment, mostly in combination with other analgesics. Overall, based on our review of the current literature, there is insufficient evidence to recommend caffeine cessation to all migraine patients, but it should be highlighted that caffeine overuse may lead to migraine chronification, and sudden caffeine withdrawal may trigger migraine attacks. Migraine sufferers should be aware of the amount of caffeine they consume and not exceed 200 mg daily. If they wish to continue drinking caffeinated beverages, they should keep their daily intake as consistent as possible to avoid withdrawal headache.

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Section: Introductionmentioning

confidence: 99%

The Ambiguous Role of Caffeine in Migraine Headache: From Trigger to Treatment

2020

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Headache Research and Medical Practice in Brazil: An Historical Overview

2015

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Since the creation of the Brazilian Headache Society in 1978, substantial developments have taken place in both research and clinical practice in the field of headache medicine in Brazil. The Society now has almost 300 members throughout the country, actively working to improve the health of the general population and, in particular, diagnose and treat headache disorders. In addition, in a few large cities, such as São Paulo, Rio de Janeiro, Recife, Ribeirão Preto, Curitiba, and Porto Alegre, headache specialists have come together to promote research projects and increase knowledge in the field through MSc, PhD, and postdoctoral programs. Furthermore, scientific journals have emerged and books have been published to record and disseminate Brazilian scientific production in headache medicine. In this narrative review, we will briefly describe some important aspects of headache medicine in Brazil from prehistoric times to the present day, discuss the origin of headache medicine as a specialty in Brazil, the principal publications dealing with headache disorders, the use of plants and other unconventional forms of treatment used by faith healers, the main training centers, and the research produced to date by Brazilians. In conclusion, in recent years enormous progress has been made in headache medicine in Brazil stimulating us to review and expand our role in an increasingly international scenario.

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Fatores associados ao uso excessivo de medicação sintomática em pacientes com enxaqueca crônica

Abstract: This study has shown a significant association among chronic migraine and medication overuse with lifetime mood and anxiety disorders in patients of the studied population. No association was found for other researched psychiatric disorders.

Cited by 2 publications

References 31 publications

The Ambiguous Role of Caffeine in Migraine Headache: From Trigger to Treatment

The Ambiguous Role of Caffeine in Migraine Headache: From Trigger to Treatment

Headache Research and Medical Practice in Brazil: An Historical Overview

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