2011
DOI: 10.1590/s1679-45082011md1914
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Abstract: The Nomenclature Committee for Factors of the HLA System of the World Health Organization standardizes the nomenclature of the HLA system and meets regularly during the International Histocompatibility Workshops. During the 15th International Histocompatibility Workshop in Buzios (RJ), Brazil, in September 2008, there was a meeting of the nomenclature committee when new rules were established, which were implemented in April 2010.

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“…Two of these immunoglobulins, HLA class I histocompatibility antigen (HLA-A) and zinc-alpha-2-glycoprotein precursor (AZGP1), are known to be involved in antigen processing and presentation, as well as graft-vs. -host disease and, are related to neuroinflammation. HLA is the expression product of the major histocompatibility complex (MHC) and participates in the immune response by presenting peptides derived from the endoplasmic reticulum lumen ( 53 ). When the blood–brain barrier is damaged, it is penetrated by immune cells in the peripheral circulation and interacts with glial cells and neurons expressing MHC, resulting in the persistence of the immune response, interfering with the normal development of the nervous system, and leading to ASD.…”
Section: Discussionmentioning
confidence: 99%
“…Two of these immunoglobulins, HLA class I histocompatibility antigen (HLA-A) and zinc-alpha-2-glycoprotein precursor (AZGP1), are known to be involved in antigen processing and presentation, as well as graft-vs. -host disease and, are related to neuroinflammation. HLA is the expression product of the major histocompatibility complex (MHC) and participates in the immune response by presenting peptides derived from the endoplasmic reticulum lumen ( 53 ). When the blood–brain barrier is damaged, it is penetrated by immune cells in the peripheral circulation and interacts with glial cells and neurons expressing MHC, resulting in the persistence of the immune response, interfering with the normal development of the nervous system, and leading to ASD.…”
Section: Discussionmentioning
confidence: 99%