ABSTRACT:The serum kinetics of Calloselasma rhodostoma (Malayan pit viper) venom -specifically two of its components, the major hemorrhagin (rhodostoxin) and a thrombin-like enzyme -was examined in a rabbit by double-sandwich enzymelinked immunosorbent assay (ELISA). The animal received intramuscularly a 1.0-mg/kg dose of C. rhodostoma venom. The venom level in serum peaked 12 hours after the injection, followed by a gradual decline and finally reached low rates 72 hours after administration. The serum kineti…
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