2006
DOI: 10.1590/s1678-91992006000100006
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Abstract: Many toxins from scorpion venoms cause neurotransmitters release by activating the autonomic system. The aim of the present work was to determine osmotic fragility of red blood cells (RBCs) and serum biochemical changes produced by the venom of Odonthobuthus doriae (O. doriae), a dangerous species of scorpion in Iran. For this study we selected 2 groups, each one containing 10 New Zealand white rabbits weighing 2 ± 0.2 kg. In vivo and in vitro osmotic fragilities as well as packed cell volume (PCV) were… Show more

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Cited by 9 publications
(5 citation statements)
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“…The response to fail is caused by an increase in cardiac output. A direct effect of scorpion venom on myocardium has been shown in several studies [128, 130, 131, 133, 140142]. Aspartate aminotransferase (AST) is distributed to all parts of the body but mostly concentrates in the liver and the heart.…”
Section: Organ Dysfunction and The Inflammatory Responsementioning
confidence: 99%
“…The response to fail is caused by an increase in cardiac output. A direct effect of scorpion venom on myocardium has been shown in several studies [128, 130, 131, 133, 140142]. Aspartate aminotransferase (AST) is distributed to all parts of the body but mostly concentrates in the liver and the heart.…”
Section: Organ Dysfunction and The Inflammatory Responsementioning
confidence: 99%
“…It may be acting (1) at the enzymatic level (2) targeting the cellular signaling molecules. Envenoming by different scorpions had shown an increase level of circulating enzyme like succinate dehydrogenase, creatine phosphokinase, lactate dehydrogenase ALT, and AST [10,[30][31][32][33][34][35][36]. These studies also confirmed that scorpion venom target the major organs (liver, kidney, muscle) and produce multi organ failure before death.…”
Section: Discussionmentioning
confidence: 79%
“…These findings were in accordance with the results of Mohammed et al (2009) who observed increase in hemoglobin level and hematocrit value in severe cases of scorpion envenomation in their study. Radha and Zare (2002) and Mirakabadi et al (2006) explained the rise of hemoglobin by hemoconcentration which occurred because of massive release of catecholamines and angiotensin II producing significant decrease in the blood volume and an increase in the extravascular fluid, leading eventually to peripheral circulatory failure and pulmonary edema. On the other side, Emam et al (2008) found decrease in hemoglobin level among their patients.…”
Section: Discussionmentioning
confidence: 99%