Mesobuthus eupeus scorpionism in Sanliurfa region of Turkey

Scorpion stings are a public health problem in Morocco, especially among children, who experience the most severe cases. Epidemiological and clinical findings on scorpion stings in Fez, Morocco, were evaluated in this investigation. Of 163 cases that required medical attention, 62.6% were male children. The mean age of patients was 4.8 ± 3.4 years. The mean time between stings and first medical attention was 3.36 ± 2.5 hours. Almost all cases occurred in the summer (94%) and extremities represented the most frequent sting sites (86.5%). Local pain, hyperemia, scarification, vomiting, sweating, restlessness, tachycardia and tachypnea were the observed clinical symptoms. Regarding severity, 55.2% of patients belonged to class III, followed by class II (26.4%) and class I (18.4%). None of our patients received antivenom; however, all of them were treated symptomatically depending on clinical manifestations.

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“…Like other works, the present work shows that the sting frequency increases in the warmest months throughout the globe (16,23,(26)(27)(28)). …”

Section: Discussionsupporting

confidence: 86%

Epidemiological and clinical characteristics of scorpion stings in children in fez, Morocco

Abourazzak¹,

Achour²,

Arqam³

et al. 2009

J. Venom. Anim. Toxins incl. Trop. Dis

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“…The venom is not as potent as that of other buthid species but still causes intense pain, hyperemia, swelling, and a burning sensation in the affected area [136]. Similarly to that of other scorpions, M. eupeus venom contains various substances that specifically interact with plasma membrane constituents.…”

Section: Novel Antimalarialsmentioning

confidence: 99%

Exploring the global animal biodiversity in the search for new drugs – Spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes

Mans¹

2017

J Transl Sci

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Drug discovery and development programs have historically mainly focused on plants with medicinal properties and the extensive knowledge of traditional healers about these plants. More recently, the vast array of marine invertebrates and insects throughout the world have been recognized as additional sources for identifying unusual lead compounds to obtain structurally novel and mechanistically unique therapeutics. The results from these efforts are encouraging and have yielded a number of clinically useful drugs. However, many arthropods other than insects -such as spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes -also produce hundreds of bioactive substances in their venom that may become useful in the clinic. Many of these chemicals are defensive and predatory weapons of these creatures and have been refined during millions of years of evolution to rapidly and with high specificity and high affinity shut down critical molecular targets in prey and predators. Exploration of these compounds may lead to the development of, among others, novel drugs for treating diseases caused by abnormalities in humans in the same (evolutionary conserved) molecular targets such as erectyle dysfunction, botulism, and autoimmune disorders, as well as the identification of novel antineoplastic, antimicrobial, and antiparasitic compounds. This paper addresses the importance of bioactive compounds from spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes to these advances.

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“…There are only a few epidemiological and clinical records of case reports involving Mesobuthus eupeus and Androctonus crassicauda, as well as scorpionism in children in the western and southeastern parts of Turkey (5,(32)(33)(34)(35)(36)(37). Adiguzel …”

Section: Epidemiological and Clinical Data On Scorpionism In Turkeymentioning

confidence: 99%

“…The local symptoms most commonly reported included local pain, edema, hyperemia, swelling, burning, numbness and itching, whereas systemic symptoms consisted of dry mouth, thirst, sweating, hypotension, hypertension, cramps, tremor, nausea, vomiting, breathing difficulty, tachycardia, sialorrhea, restlessness, hemolytic-uremic syndrome, cyanosis, cardiac failure and/or acute pulmonary edema, and death (33)(34)(35)(36)(37)(39)(40)(41)(42). In a study carried out in 2005, a total of 24,261 cases of scorpion sting were reported (42).…”

Section: Clinical Aspectmentioning

confidence: 99%