2005
DOI: 10.1590/s1678-91992005000300012
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Abstract: Visceral leishmaniasis is a zoonotic disease caused by parasites of the Leishmania genus. Dog is the major source of infection to man, especially in urban areas. The authors report a case of visceral leishmaniasis in a pit bull female dog from Bocaina, São Paulo, Brazil. The animal presented clinical signs compatible with leishmaniasis, including skin lesions in the body and partial damage of the external ears. The indirect fluorescent antibody test (IFAT) demonstrated a titer of 1280, and promastigote forms o… Show more

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Cited by 8 publications
(5 citation statements)
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“…), but was only significant difference at 80 day in infected and treated groups. Generally, , it was noticed an increased concentration Azotemia (high serum values of urea and creatinine) of infected mice, this result agrees with several authors ( Ferrer, et al, 1992;Kontos & Koutinas, 1993;Denerolle, 1996 ;Ciaramella, et al, 1997;Slappendel & Ferrer, 1998;Solano-Gallega, et al, 2001;Langoni, et al, 2005 andJoshi, et al, 2006). However, some studies disagree with our data on the serum urea and creatinine levels that are usually normal (Pagliano, et al, 2005;Bhattacharya, et al, 2006 andLópez-Peña, et al,2009(. In the present study, in kidneys of infected mice with VL was observed hemorrhages, destruction in some renal tubules, lymphocyte infiltrations glomerular inflammation, glomerular tuft was increased, intravascular accumulations of neutrophils and monocytes, destructions of Bowman's capsule, diffuse chronic interstitial inflammation.…”
Section: Introductionsupporting
confidence: 89%
“…), but was only significant difference at 80 day in infected and treated groups. Generally, , it was noticed an increased concentration Azotemia (high serum values of urea and creatinine) of infected mice, this result agrees with several authors ( Ferrer, et al, 1992;Kontos & Koutinas, 1993;Denerolle, 1996 ;Ciaramella, et al, 1997;Slappendel & Ferrer, 1998;Solano-Gallega, et al, 2001;Langoni, et al, 2005 andJoshi, et al, 2006). However, some studies disagree with our data on the serum urea and creatinine levels that are usually normal (Pagliano, et al, 2005;Bhattacharya, et al, 2006 andLópez-Peña, et al,2009(. In the present study, in kidneys of infected mice with VL was observed hemorrhages, destruction in some renal tubules, lymphocyte infiltrations glomerular inflammation, glomerular tuft was increased, intravascular accumulations of neutrophils and monocytes, destructions of Bowman's capsule, diffuse chronic interstitial inflammation.…”
Section: Introductionsupporting
confidence: 89%
“…CVL occurs as a chronic, fatal and systemic disease. The major clinical signs consist of cachexia, hypergammaglobulinemia, hepatosplenomegaly, anemia, and lymphadenopathy (7)(8)(9)(10)(11)(12).…”
Section: Introductionmentioning
confidence: 99%
“…5 A RIFI, utilizada a partir da década de 60, indicada pelo Ministério da Saúde para o diagnóstico e levantamento epidemiológico para leishmaniose, apresenta elevadas sensibilidade (90-100%) e especificidade (80%). 6,7,8,9 Uma das principais limitações da RIFI é a ocorrência de reações cruzadas, principalmente com a doença de Chagas. Os antígenos utilizados nos testes diagnósticos de RIFI e ELISA são geralmente derivados de promastigotas de cultura, parasitos intactos ou moléculas solúveis.…”
Section: Introductionunclassified