Calcium glycerophosphate supplemented to soft drinks reduces bovine enamel erosion

Barbosa, Célia Marisa Rizzatti; Montagnolli, L. G.; Kato, Melissa Thiemi; Sampaio, Fábio Correia; Buzalaf, Marília Afonso Rabelo

doi:10.1590/s1678-77572012000400004

Cited by 18 publications

(12 citation statements)

References 13 publications

(17 reference statements)

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“…Soft drink Coca-Cola ® (Jundiaí, São Paulo, Brazil) was selected for this study because in previous studies it presented (1,2) the lowest pH among all soft drinks evaluated. The pH of 4 bottles of Coca-Cola ® (Jundiaí, São Paulo, Brazil) used in the study was measured with the colorimetric tape and the value found for all was pH = 2.0.…”

Section: Thismentioning

confidence: 99%

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Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Almenara

Rebouças

Cavalli

et al. 2016

Pesqui. bras. odontopediatria clín. integr.

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Objective: To evaluate the influence of Coca-Cola ® consumption on the salivary pH of 12-year old children. Material and Methods: The convenience sample was composed of forty-five 12-year old students of both genders from public schools of Itatiba, state of São Paulo, Brazil. Salivary pH was measured with pH colorimetric tape indicator (Merck). The reading of the colorimetric method was made by an experienced evaluator under uniform lighting conditions. The colorimetric tape was positioned in the back of the student's tongue, which remained with the mouth shut for 30 Seconds. For control, the first measurement (T0) was performed before the intake of the soft drink (baseline pH). Subsequently, students were instructed to slowly drink 100 ml of Coca-Cola ® using a plastic disposable cup. Immediately after ingestion, the pH was measured again with the colorimetric tape (t1). The oral pH values were also measured 5 minutes (t2), 10 minutes (t3) and 15 minutes (t4) after the soft drink intake, keeping the tape positioning always the same in all measurements. The statistical SAS software was used for data analysis. Comparisons of oral pH values at different times were performed by the Tukey-Kramer test adopting 5% significance level. Results: Immediately after soft drink intake, the salivary pH significantly decreased (pH = 6.26) (p <0.05) compared to baseline (pH = 7.23) (p <0.05). Fifteen minutes after ingestion, although an increase in the pH was observed (pH = 6.64), it had not yet returned to baseline (T0) (p <0.05). Conclusion: Coca-Cola ® intake caused a significant reduction in salivary pH, without, however, reaching critical pH for enamel demineralization.

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Section: Thismentioning

confidence: 99%

“…However, with the epidemiological reduction in caries prevalence observed in recent decades, dental elements are kept for a longer period in the oral cavity, making them more susceptible to the development of other types of injuries, such as tooth erosion [2].…”

Section: Introductionmentioning

confidence: 99%

Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Almenara

Rebouças

Cavalli

et al. 2016

Pesqui. bras. odontopediatria clín. integr.

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“…As shown, this could be realised only under an endogenous supply of the ions [34,35,51]. The concentration of the ions in the mixed saliva ought to exceed the concentration in the hydrate layer of enamel in order to provide an efficient process of diffusion from the surface of enamel [1,14].…”

Section: Discussionmentioning

confidence: 99%

“…These processes prove to be a consequence of the changes in mineral-organic of the plaque fluid and mixed saliva. However, the molecular composition of these substances can be altered due to the intake of special preventive drugs (endogenous prophylaxis) on the basis of calcium phosphates [16,17,20,30,31], in particular, the endogenous prophylactic calcium glycerophosphate [32][33][34][35]. The use of such preventive drugs can achieve optimal concentrations of calcium and phosphate in mixed human saliva, however, possible changes in composition have not been considered.…”

Section: +mentioning

confidence: 99%

Does dentifrice provide the necessary saturation of ions in oral fluids to favour remineralisation?

Seredin¹,

Goloshchapov²,

Yuri³

et al. 2018

Russ Open Med J

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Background -Changes in the molecular composition of mixed human saliva using endogenous and exogenous methods of caries prevention were studied and the duration of these changes in relation to the initial state of the oral fluid was determined. Material and Methods -In total, 200 European healthy, addiction-free, university-educated males and females, aged 22-30 were recruited for the study. Participants collected their mixed saliva samples after the use of a multi-mineral toothpaste (exogenous prevention) and after three days of taking a calcium glycerophosphate tablet (endogenous prevention). In the first stage of the study, samples of mixed saliva were analysed by infrared (IR) lab spectrometer and equipment of infrared microspectroscopy beamline at the Australian Synchrotron (Victoria, Australia) was used in the second stage of study. Results -Based on the experimental data obtained by IR-spectroscopy technique, the mineral/organic and carbon/phosphate ratios were calculated. The changes in the organic mineral balance of the oral cavity induced by these two preventive methods were analysed. The statistical significance of the results for the confidence level of p is indicated. The data shows that changes in the molecular composition of mixed saliva when using an exogenous method of caries prevention only provides a short-term effect, continuing for the first 30 minutes after the preceding prevention. Moreover, calcium glycerophosphate tablets can change the organic-mineral balance in mixed saliva, increasing the content of mineral groups and complexes. The content of endogenous, biologically accessible phosphate groups and complexes in the mixed saliva exceeds by approximately 12% that of the mixed saliva before the use of the prevention agents. Conclusion -Use of calcium glycerophosphate tablets in combination with brushing (a combination of endogenous and exogenous prevention methods) leads to the long-term presence of high concentrations of ions, mineral complexes and groups (phosphates) in the oral fluid.

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“…Outros materiais bioativos como o fosfato de cálcio amorfo, a caseína fosfopeptídica associada ao fosfato de cálcio amorfo (Poggio et al, 2013), biovidros de fosfosilicato de cálcio e sódio (Turssi et al, 2011), glicerofosfato de cálcio (Barbosa et al, 2012), bicarbonato de arginina e carbonato de cálcio (Faller; Eversole, 2013) têm sido usados como agentes desensibilizantes e remineralizantes.…”

Section: Introductionunclassified

Efeito de materiais contendo compostos bioativos na remineralização de lesões de erosão no esmalte bovino: estudo in vitro

Pedrosa¹

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Calcium glycerophosphate supplemented to soft drinks reduces bovine enamel erosion

Cited by 18 publications

References 13 publications

Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Influence of Soft Drink Intake on the SalivarypH of Schoolchildren

Does dentifrice provide the necessary saturation of ions in oral fluids to favour remineralisation?

Efeito de materiais contendo compostos bioativos na remineralização de lesões de erosão no esmalte bovino: estudo in vitro

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