2011
DOI: 10.1590/s1677-55382011000600028
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Abstract: Background: The objectives of this study were to determine the frequency of metastatic (M1) prostate cancer (PC) at presentation in different age groups, to examine the association of age with PC-specific mortality, and to calculate the relative contribution of different age groups to the pool of M1 cases and PC deaths. Methods: Records from 464,918 patients who were diagnosed with PC from 1998 to 2007 were obtained from the Surveillance, Epidemiology, and End Results (SEER) database. The patients were categor… Show more

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Cited by 40 publications
(52 citation statements)
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“…In the context of PCa, each year the SEER registry provides data on the numbers of new cases diagnosed and deaths that occurred in the current year in the USA [46,47]. From population-based registries, data on the baseline characteristics of patients included might be used to analyze temporal trends in PCa presentation and risk [48][49][50][51]. In the five Nordic countries, an analysis of incidence and mortality data revealed a rapid increase in PCa incidence during the early 1990s coinciding with the introduction of PSA testing, while mortality rates stabilized or declined in countries where PSA testing and curative treatment have been commonly practiced since the late 1980s [52].…”
Section: 4mentioning
confidence: 99%
“…In the context of PCa, each year the SEER registry provides data on the numbers of new cases diagnosed and deaths that occurred in the current year in the USA [46,47]. From population-based registries, data on the baseline characteristics of patients included might be used to analyze temporal trends in PCa presentation and risk [48][49][50][51]. In the five Nordic countries, an analysis of incidence and mortality data revealed a rapid increase in PCa incidence during the early 1990s coinciding with the introduction of PSA testing, while mortality rates stabilized or declined in countries where PSA testing and curative treatment have been commonly practiced since the late 1980s [52].…”
Section: 4mentioning
confidence: 99%
“…In their analyses, data indicates that, compared with younger patients (aged < 75 years), older patients were more likely to present with very advanced disease and contributed almost half (48%) of all M1 cases [2].…”
Section: Discussionmentioning
confidence: 99%
“…Screening may increase chances of disease detection in early stages, however, despite all debates about this matter, PC is often discovered in advanced stages in about to 17% of patients, in which the risk of cancer-specific mortality is increased [2].…”
Section: Introductionmentioning
confidence: 99%
“…However, in patients with advanced disease, PCa is usually symptomatic and most of these patients will ultimately die of their disease. To determine the frequency of metastatic prostate cancer in different age groups, records from 464,918 patients who were diagnosed with PCa were obtained from the Surveillance, Epidemiology, and End Results (SEER) database [2]. Patients were categorized into age groups ranging from <50 to ≥90 years.…”
Section: Do Elderly Men Benefit From Early Detection Of Prostate Cancer?mentioning
confidence: 99%