Juxtaglomerular cell tumor as a rare cause of hypertension in adults

Chambô, José Luiz; Júnior, Renato Falci; Lucon, Antônio Marmo

doi:10.1590/s1677-55382004000200006

Cited by 9 publications

(1 citation statement)

References 3 publications

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“…Other commonly reported symptoms include headache, polyuria, nocturia, dizziness and vomiting. Patients almost invariably are hypertensive at initial examination due to high plasma renin activity secreted by the tumor [7,8]. Converting enzyme inhibitors are usually effective to the hypertension, whereas other commonly used antihypertensive agents are hard to control the constant marked hypertension.…”

Section: Discussionmentioning

confidence: 99%

The diagnosis and surgical management of juxtaglomerular cell tumor of the kidney

Dong¹,

Li²,

Yan³

et al. 2010

Journal of Hypertension

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Juxtaglomerular cell tumor (JCT) of the kidney is a rare benign renal neoplasm. Four cases of JCT of the kidney have been diagnosed and treated surgically in our hospital from January 2005 to August 2008. The clinical features, laboratory examination, imaging examination, pathological results and electron microscopy examination were analyzed, and a review of the literature was summarized. Three patients underwent open partial nephrectomy, and one patient underwent laparoscopic partial nephrectomy. Pathological examination confirmed the final diagnosis of JCT of the kidney. The blood pressure, potassium, renin and aldosterone remained within the normal range after surgery. JCT of the kidney should be kept in mind because they represent a surgically curable cause of secondary hypertension. Nephron-sparing surgery is recommended.

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Section: Discussionmentioning

confidence: 99%

The diagnosis and surgical management of juxtaglomerular cell tumor of the kidney

Dong¹,

Li²,

Yan³

et al. 2010

Journal of Hypertension

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Juxtaglomerular cell tumor in an 8‐year‐old girl

Shao

Manalang

Cooley

2006

Pediatric Blood & Cancer

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Juxtaglomerular cell tumor (JGCT) is an extremely rare renal neoplasm in the pediatric population. It is considered a benign tumor arising from the juxtaglomerular apparatus of the kidney. JGCT has characteristic clinicopathologic features, but its cytogenetic features are unknown. We report a case of JGCT in an 8-year-old female who presented with severe hypertension, elevated serum renin level, and a well circumscribed tumor in the right kidney. Protogranules of renin was identified in the cytoplasm of the tumor cells by electron microscopic examination. Fluorescence in situ hybridization revealed monosomy of chromosomes X, 6, 9, 11, 15, and 21.

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At the bottom of the differential diagnosis list: unusual causes of pediatric hypertension

Grinsell

Norwood

2008

Pediatr Nephrol

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Hypertension affects 1-5% of children and adolescents, and the incidence has been increasing in association with obesity. However, secondary causes of hypertension such as renal parenchymal diseases, congenital abnormalities and renovascular disorders still remain the leading cause of pediatric hypertension, particularly in children under 12 years old. Other less common causes of hypertension in children and adolescents, including immobilization, burns, illicit and prescription drugs, dietary supplements, genetic disorders, and tumors will be addressed in this review.

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Juxtaglomerular cell tumor as a rare cause of hypertension in adults

Cited by 9 publications

References 3 publications

The diagnosis and surgical management of juxtaglomerular cell tumor of the kidney

The diagnosis and surgical management of juxtaglomerular cell tumor of the kidney

Juxtaglomerular cell tumor in an 8‐year‐old girl

At the bottom of the differential diagnosis list: unusual causes of pediatric hypertension

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