Special strategies and management of urological diseases during the COVID-19 Pandemic: initial experiences from a Medical Center of China

Chen, Wei; Wang, Xiao Meng; Fu, Guang Qing; Zeng, Xiang; Wu, Caifang; Liang, Yong; Liu, Jian Hui; Teoh, Jeremy Yuen Chun

doi:10.1590/s1677-5538.ibju.2020.s102

Cited by 4 publications

(1 citation statement)

References 8 publications

(8 reference statements)

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“…Special strategies should be used to treat urological conditions during the COVID-19 pandemic, keeping in mind the golden rule for any infectious disease at any time: "prevention is better than cure." [45].…”

Section: Pandemic Considerationsmentioning

confidence: 99%

The at-home delivery of treatment for benign prostate enlargement and chronic prostatitis enabled by Dr Allen’s Device is a valuable healthcare innovation during a pandemic

Adjani

Allen

2021

Medico Research Chronicles

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Introduction:The Coronavirus (COVID-19) outbreak has demonstrated the need for a novel delivery of treatment for benign prostate enlargement (BPE) and chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS). Their standard treatments with medications and surgeries require extensive contact between patients and healthcare professionals that worsens a pandemic. This study aims to determine whether therapeutic Dr Allen's Device (DATD) and Thermobalancing therapy (TT) can be used as an effective self-management tool and athome treatment for chronic prostate diseases. Methods: This is a retrospective cohort study of 45 men with CP/CPPS and 124 men with BPE who were observed before and after applying TT with DATD at home for 6 months in 2 clinical controlled trials. The dynamics of clinical characteristics and parameters, such as pain, urinary symptoms, quality of life (QoL), and prostate volume (PV) were compared to the control groups without DATD. Results: DATD reduced pain scores from 10.3 to 3.5 (P<0.001) in men with CP/CPPS. In men with BPE, DATD reduced PV from 45mL to 31mL (P<0.001) and urinary symptoms from 14.3 to 4.9 (P<0.001). DADT significantly improved QoL in both treatment groups. In the control groups, no positive changes were observed. Conclusions: The use of DATD with TT relieves chronic pelvic pain and reduces an abnormal prostate size in patients with CP/CPPS and BPE, improving their QoL and wellbeing. Thus, DATD is an effective at-home self-management tool and provides a novel delivery of treatment for non-cancerous prostatic diseases, especially important during a pandemic.

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Section: Pandemic Considerationsmentioning

confidence: 99%

The at-home delivery of treatment for benign prostate enlargement and chronic prostatitis enabled by Dr Allen’s Device is a valuable healthcare innovation during a pandemic

Adjani

Allen

2021

Medico Research Chronicles

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Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

Farshbafnadi

Zonouzi

Sabahi

et al. 2021

Experimental Gerontology

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The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been determined that the old population are not only at an increased risk for affliction with COVID-19 infection, but also atypical presentations, severe forms of the disease, and mortality are more common in this population. A plethora of mechanisms and risk factors contribute to the higher risk of infection in the old population. For instance, aging is associated with an increment in the expression of Angiotensin-Converting Enzyme-2 (ACE-2), the receptor for SARS-CoV-2 spike protein, which precipitates replication of the virus in the old population. On the other hand, immune dysregulation and changes in gut microbiota as a result of aging can contribute to the cytokine storm, one of the main indicators of disease severity. Decrement in sex steroids, especially in women, as well as growth hormone, both of which have crucial roles in immune regulation, is a key contributor to disease severity in old age. Senescence-associated oxidative stress and mitochondrial dysfunction in both pneumocytes and immune cells contribute to the severity of infection in an exacerbative manner. In addition, lifestyle-associated factors such as nutrition and physical activity, which are compromised in old age, are known as important factors in COVID-19 infection. Aging-associated comorbidities, especially cardiovascular diseases and Diabetes Mellitus, also put older adults at an increased risk of complications, and disease severity.

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Urological tumors treatment in Brazil during the SARS-Cov-2 outbrake

Favorito

2021

Int. braz j urol.

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SARS-CoV-2 pandemic has a great impact in all medical fields and the paper of Anjos Silva and Collegues from Brazil (1) shows interesting data about surgery in patients with urological tumors. Previous studies shows that SARS-CoV-2 changes the urologic practice in several fields (2-5), but the treatment of urological tumors during the outbreak has specially importance (6-8). In this interesting paper the authors studied if uro-oncological surgeries at pandemic are safe in a cohort of 213 patients (161 patients were submitted to elective surgery and 44 to emergency surgery) in a reference hospital in Brazil and concluded that Elective uro-oncological procedures at the COVID-19 epidemic period in a COVID-19-free Institute are safe, and patients who need urgent procedures, with a long period of hospitalization, need special care to avoid COVID-19 infection and its outcomes.

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Special strategies and management of urological diseases during the COVID-19 Pandemic: initial experiences from a Medical Center of China

Cited by 4 publications

References 8 publications

The at-home delivery of treatment for benign prostate enlargement and chronic prostatitis enabled by Dr Allen’s Device is a valuable healthcare innovation during a pandemic

The at-home delivery of treatment for benign prostate enlargement and chronic prostatitis enabled by Dr Allen’s Device is a valuable healthcare innovation during a pandemic

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

Urological tumors treatment in Brazil during the SARS-Cov-2 outbrake

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