2013
DOI: 10.1590/s1677-5538.ibju.2013.05.03
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Abstract: Introduction: The aim of this study was to compare overall survival in elderly patients (≥ 80 years) with muscle-invasive bladder cancer (MIBC) undergoing either radical cystectomy (RC) or conservative treatment. Material and Methods:We performed a retrospective, comparative analysis of overall-and cancer-specific survival in octagenarians with MIBC (> pT2) submitted to RC or conservative treatment. Uni-and multivariable Cox regression analysis were performed to assess predictors of overall survival. Cumulativ… Show more

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Cited by 15 publications
(9 citation statements)
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References 14 publications
(17 reference statements)
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“…Similarly to the finding of the present study, the 2-year OS rate in octogenarians who underwent RC ranges from 40 to 60% [20,21,[25][26][27]. These data justify the use of RC in well-selected very elderly patients not only to prolong survival but also to prevent the consequences of local complications due to tumor progression (pelvic pain, bleeding, blood transfusions, hemostatic trans-urethral procedures, and percutaneous nephrostomy).…”
Section: Discussionsupporting
confidence: 84%
See 1 more Smart Citation
“…Similarly to the finding of the present study, the 2-year OS rate in octogenarians who underwent RC ranges from 40 to 60% [20,21,[25][26][27]. These data justify the use of RC in well-selected very elderly patients not only to prolong survival but also to prevent the consequences of local complications due to tumor progression (pelvic pain, bleeding, blood transfusions, hemostatic trans-urethral procedures, and percutaneous nephrostomy).…”
Section: Discussionsupporting
confidence: 84%
“…According to the literature, we mainly used the age-adjusted CCI and the ASA classification to estimate the risk of morbidity and mortality of our patients [26]. However, elderly patients in general, and octogenarians in particular, merit a more detailed preoperative evaluation including assessment of functional status, nutrition, comorbidities, weight loss, exhaustion, weakness, muscle wasting status, and daily physical activity.…”
Section: Discussionmentioning
confidence: 99%
“…Indeed, 69% of all our patients are alive with no evidence of cancer and with intact well-functioning urinary bladder at median follow-up of 37 months. These figures are similar to those observed in large surgical series and other bladder preservation reports [ 8 9 ].…”
Section: Discussionsupporting
confidence: 92%
“…Bladder cancer is one of the most common urologic malignancies in men with an especially high incidence in the elderly patients (1). Radical cystectomy (RC) with urinary diversion is a standard surgical measure in Urology and constitutes the golden choice for muscle-invasive bladder cancer (MIBC).…”
Section: Introductionmentioning
confidence: 99%