2013
DOI: 10.1590/s1677-5538.ibju.2013.03.13
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Abstract: Introduction: Published data suggest that patients with acromegaly have an increased prevalence of prostate disorders. Objective: To evaluate prostatic disorders in acromegalic patients comparing these results after one year of treatment of acromegaly and with a group of healthy men. Materials and Methods: This study was composed of two parts: sectional study comparing patients with healthy controls (baseline) and prospective, longitudinal study (at baseline and after one year of treatment). Forty acromegalic … Show more

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Cited by 7 publications
(13 citation statements)
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“…This is evident by IGF1 signalling conferring stimulatory effect on androgenic receptor by attenuating forkhead box-containing protein O subfamily (Foxo1) inhibition (29). In our study, prostatic enlargement was significantly higher among patients with acromegaly than controls, which is in consonance with other studies (19,30). This was irrespective of age and disease activity or gonadal status in contrast to study reported by Correa et al (19).…”
Section: European Journal Of Endocrinologysupporting
confidence: 92%
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“…This is evident by IGF1 signalling conferring stimulatory effect on androgenic receptor by attenuating forkhead box-containing protein O subfamily (Foxo1) inhibition (29). In our study, prostatic enlargement was significantly higher among patients with acromegaly than controls, which is in consonance with other studies (19,30). This was irrespective of age and disease activity or gonadal status in contrast to study reported by Correa et al (19).…”
Section: European Journal Of Endocrinologysupporting
confidence: 92%
“…The structural changes found in the prostate of patients with acromegaly in our study were similar to these noted in previous studies (7,19). Prostatic histopathology revealed BPH in six of 14 (43%) patients.…”
Section: European Journal Of Endocrinologysupporting
confidence: 91%
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