Tratamento de gestantes com epilepsia: papel dos medicamentos antiepilépticos clássicos e novos

Hirama, Sheila Cristina; Dias, Bianca de Cássia Sant'Anna; Matsudo, Evelyn Toshie; Gandolfo, Carolina Giardini; Gandolfo, Cláudia Giardini; Ferreira, Beatriz Cristine Guimarães; Albuquerque, Marly de

doi:10.1590/s1676-26492008000400008

Cited by 3 publications

(4 citation statements)

References 77 publications

(93 reference statements)

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“…There is also a classification according to the affected brain area, called partial/focal (only one area of the brain) or generalized (the whole brain). The generalized crisis was observed in this report, since it is responsible for triggering seizures, i.e., seizures with motor involvement and loss of consciousness, Eyes on Health Sciences V.02 Follow-up of a postoperative pregnant woman with low-grade oligodendroglioma usually related to the cerebral cortex, where the tumor developed infiltrative characteristics 13,14,15,24,25 . Epilepsy can only be considered cured if there is no recurrence of seizures within 2 years, with therapeutic weaning without recurrence, or with surgical resolution28.…”

Section: Evenmentioning

confidence: 69%

Follow-up of a postoperative pregnant woman with low-grade oligodendroglioma

Rampazzio,

Lopez,

Angelo

et al. 2024

Eyes on Health Sciences V.02

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Central Nervous System (CNS) neoplasms do not usually comprise the epidemiological profile of women of childbearing age, affecting more men in a ratio of 2:1 in the fourth or fifth decade of life. There is no consensus in the literature on risk factors and related family history in relation to the individual's gender, however, some studies suggest a neuroprotection deficit due to the absence of estrogen, which, in women, could be related to the indiscriminate use of hormonal contraceptives alone, such as capsules and/or progesterone injections, since estrogen has been proven to play an important role in the deployment of central nervous system cells. The symptomatology secondary to grade II oligodendrogliomas usually refers to epilepsy and headache, which are accompanied by little improvement to medications. Resolution, in this case, consists of surgical tumor resection and usually has a good prognosis when diagnosed early. In the cases of young women diagnosed with oligodendrogliomas and undergoing a well-disciplined clinical-surgical therapy, family planning is possible and of great importance. They usually have uneventful gestational development and a smooth delivery, as long as they are assisted by a multidisciplinary team. To this end, physicians must take advantage of scientific evidence that supports the use of medications and the choice of imaging method to monitor the evolution of the case. In cases of malignant CNS neoplasia, local chemotherapy may be an option. Surgical reapproach should be considered with great caution and the decision should always prioritize the health of the mother over that of the developing fetus.

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Section: Evenmentioning

confidence: 69%

Follow-up of a postoperative pregnant woman with low-grade oligodendroglioma

Rampazzio,

Lopez,

Angelo

et al. 2024

Eyes on Health Sciences V.02

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“…The category "D" medications include antiepileptics. The use of phenytoin, carbamazepine, valproate, lamotrigine, and phenobarbital has been associated with an increased risk for the development of major malformations or morphological abnormalities (Hirama et al, 2008). In the study by Guerra et al (2008), of the four pregnant women who used medications included in risk category D, two had been suffering from epilepsy, one was using phenobarbital alone, and the other, together with carbamazepine, both prescribed throughout the pregnancy period.…”

Section: Discussionmentioning

confidence: 99%

“…Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas/ 78 complications and maternal-fetal malformations (Hirama et al, 2008).…”

Section: Ethno-epidemiological Study Of Pregnant Womenunclassified

Ethno-epidemiological study of medicinal products and medicinal plants use among pregnant women

Matta¹,

Borges²,

Landi³

et al. 2021

BLACPMA

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The objective of this study was to examine the profile of pregnant women who visited the Unified Health System of the municipality of Umuarama/PR and to analyze their use of drugs categorized as D and X according to the United States Food and Drug Administration FDA and contraindicated medicinal plants for evaluating the potential gestational risks.A cross-sectional ethnoepidemiological study using a questionnaire was conducted among 500 pregnant women from January to May 2017. According to the pregnant women, during the prenatal period, 67.8% did not receive information on the use of medicinal plants and 26.6% used contraindicated plants. Among the drugs used, 12.2% belonged to category "D" (anticonvulsants), and 2.4% belonged to category "X" (hormonal contraceptives). This work highlights the need to expand health promotion activities to the basic units and implement protocols and technical guidance tools as well as training of pharmaceutical professionals to educate the population on the risk of these drugs during pregnancy.

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“…24 Em relação ao ácido acetilsalicílico existem restrições quanto ao seu uso, tem sido associado a baixo peso no nascimento e sangramentos quando usado próximo do parto. Porém a classe mais utilizada são os analgésicos, sendo que o mais recomendado é o paracetamol que possui classificação B.…”

Section: Os Medicamentos E a Gestaçãounclassified

Medicamentos e gravidez: Influência na morfologia fetal

Tacon

Amaral

Tacon

2017

RESU

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ResumoObjetivo: Conhecer os fatores associados ao uso inadequado de medicamentos no período gestacional, o que poderá ajudar na implementação de programas para esclarecer os malefícios sobre a saúde materno-fetal. Fonte de dados: este estudo de revisão pesquisou nas bases de dados Bireme, Scielo, PubMed, Lilacs e Site Up to Date. A seleção levou em conta seus títulos e resumos relacionados ao assunto, no período de 2006 a 2017, utilizando os descritores Uso de medicamentos/Drug utilization, gravidez/pregnancy e desenvolvimento fetal/fetal morphology. Foram encontrados 75 artigos, desses foram selecionados 33, os mais recentes e de alto teor teórico necessário para a construção do texto. Síntese de dados: Por meio desta análise observouse a necessidade de maior atuação dos profissionais da saúde, na tentativa de esclarecer o perigo da automedicação, do uso inadequado de medicamentos e a importância dos hábitos saudáveis. Conclusões: Para tanto, novas pesquisas na área são cada vez mais necessárias e conscientizar as gestantes quanto aos perigos de anomalias por medicação, contribuindo para a melhoria da saúde pública. Palavras-chave:Uso de medicamentos. Gravidez. Desenvolvimento fetal. AbstractObjective: To know the factors associated with the inadequate use of drugs during the gestational period, which may help in the implementation of programs to clarify the harm to maternal-fetal health. Data source: This review searched on the databases Bireme, Scielo, PubMed, Lilacs and Site Up to Date. The selection took into account its titles and abstracts related to the subject, from 2006 to 2017, using the descriptors Use of Medications / Drug utilization, pregnancy / pregnancy and fetal development / fetal morphology. We found 75 articles, of which 33 were selected, the most recent and high theoretical content required for text construction. Data synthesis: This analysis revealed the need for greater performance of health professionals in an attempt to clarify the danger of self-medication, inadequate use of medications and the importance of healthy habits. Conclusions: therefore, new research in the area is increasingly necessary and make pregnant women aware of the dangers of medication anomalies, contributing to the improvement of public health.

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Tratamento de gestantes com epilepsia: papel dos medicamentos antiepilépticos clássicos e novos

Cited by 3 publications

References 77 publications

Follow-up of a postoperative pregnant woman with low-grade oligodendroglioma

Follow-up of a postoperative pregnant woman with low-grade oligodendroglioma

Ethno-epidemiological study of medicinal products and medicinal plants use among pregnant women

Medicamentos e gravidez: Influência na morfologia fetal

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