Dieta cetogênica e dieta de Atkins modificada no tratamento da epilepsia refratária em crianças e adultos

Inuzuka, Luciana Midori

doi:10.1590/s1676-26492008000200005

Cited by 7 publications

(15 citation statements)

References 21 publications

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“…These characteristics include fatty acid composition and nutrient density [ 29 ]. There are currently four main ketogenic dietary therapies (KDTs) [ 30 , 31 ]: the classic KD (as mentioned above), the modified Atkins diet (MAD) (for obesity treatment) [ 32 ], the medium-chain triglyceride (MCT) (control of metabolic diseases) diet [ 33 ], and the low glycemic index treatment (LGIT) (treatment of intractable epilepsy) [ 30 , 34 , 35 , 36 ].…”

Section: Ketosis-inducing Diets Definition Types and Effectsmentioning

confidence: 99%

Effects of Calorie Restriction on Health Span and Insulin Resistance: Classic Calorie Restriction Diet vs. Ketosis-Inducing Diet

Napoleão¹,

Fernandes²,

Miranda³

et al. 2021

Nutrients

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As the incidence of Chronic Non-Communicable Diseases (CNCDs) increases, preventive approaches become more crucial. In this review, calorie restriction (CR) effects on human beings were evaluated, comparing the benefits and risks of different CR diets: classic CR vs. ketosis-inducing diets, including intermittent fasting (IF), classic ketogenic diet (CKD), fasting mimicking diet (FMD), very-low-calorie ketogenic Diet (VLCKD) and Spanish ketogenic Mediterranean diet (SKMD). Special emphasis on insulin resistance (IR) was placed, as it mediates metabolic syndrome (MS), a known risk factor for CNCD, and is predictive of MS diagnosis. CR is the most robust intervention known to increase lifespan and health span, with high evidence and known biochemical mechanisms. CR improves cardiometabolic risk parameters, boosts exercise insulin sensitivity response, and there may be benefits of implementing moderate CR on healthy young and middle-aged individuals. However, there is insufficient evidence to support long-term CR. CKD is effective for weight and MS management, and may have additional benefits such as prevention of muscle loss and appetite control. SKMD has extreme significance benefits for all the metabolic parameters studied. Studies show inconsistent benefits of IF compared to classic CR. More studies are required to study biochemical parameters, reinforce evidence, identify risks, and seek effective and safe nutritional CR approaches.

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Section: Ketosis-inducing Diets Definition Types and Effectsmentioning

confidence: 99%

Effects of Calorie Restriction on Health Span and Insulin Resistance: Classic Calorie Restriction Diet vs. Ketosis-Inducing Diet

Napoleão¹,

Fernandes²,

Miranda³

et al. 2021

Nutrients

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show abstract

“…Estes levam ao aumento da osmolalidade plasmática e, assim, desencadeiam a sensação de sede e o maior consumo hídrico. 15 Tal fato foi observado neste estudo, onde os grupos que receberam dieta da proteína apresentaram maior ingestão de água frente aos grupos alimentados com dieta controle (tabela 1). Adicionalmente, a excreção das cetonas pelo rim é acompanhada da excreção de sódio, o que causa aumento da diurese, fato também observado durante o experimento (dados observacionais não apresentados).…”

Section: Discussionunclassified

A “Dieta Da Proteína” Reduz O Diâmetro E a Densidade Volumétrica Glomerular Em Ratas

Ribeiro

Pascoal²,

Castro³

et al. 2016

DEMETRA

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ARTIGOS DE TEMA LIVRE / FREE THEMED ARTICLES A "dieta da proteína" reduz o diâmetro e a densidade volumétrica glomerular em ratas The "protein diet" reduces diameter and glomerular volumetric density in rats Resumo Objetivo: O objetivo deste estudo foi avaliar o efeito do consumo da dieta da proteína na morfologia do tecido renal. Métodos: Quarenta Rattus Norvegicus wistar albino, adultas, foram divididas em quatro grupos (n=10): Controle 1 (C1), Controle 2 (C2), Hiperproteico 1 (HP1) e Hiperproteico 2 (HP2). Os grupos C2 e HP2 foram submetidos à restrição alimentar de 30%. Ao final do experimento, os rins foram retirados, pesados e seu comprimento e largura, aferidos. Posteriormente, foram clivados através do método orientator, fixados em formalina e incluídos em parafina. As lâminas dos cortes histológicos foram coradas pela técnica de Hematoxilina & Eosina e fotomicrografadas. A densidade volumétrica glomerular foi determinada por método estereológico, e o diâmetro dos glomérulos renais foi calculado com auxílio do software Image J. Análises séricas foram realizadas pelo método colorimétrico. Os resultados são expressos como média e desvio padrão. Para comparação das médias entre os grupos, foram utilizados ANOVA e Tukey como pós-teste, aceitando nível de significância de 5%. Resultados: Os grupos hiperproteicos apresentaram maior pressão arterial. O tamanho e peso renal do grupo HP1 foram maiores do que C1 e C2. O grupo HP1 mostrou diâmetro glomerular inferior e o grupo HP2 mostrou densidade volumétrica glomerular inferior aos grupos C1 e C2. Conclusão: A "dieta da proteína" pode causar aumento da pressão arterial sistólica, morfologia renal anormal, redução do diâmetro e na densidade volumétrica glomerular. Assim, o estudo sugere que essa dieta possa levar a alterações no tecido renal, predispondo ao desenvolvimento de doenças crônicas.

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“…These characteristics include fatty acid composition and nutrient density [29]. There are currently 4 main Ketogenic Dietary Therapies (KDTs) [30,31]: the classic KD (as mentioned above), the Modified Atkins Diet (MAD) (treated for obesity treatment) [32], the Medium-Chain Triglyceride (MCT) (control of metabolic diseases) diet [33], and the Low Glycemic Index Treatment (LGIT) (treatment of intractable epilepsy) [30,[34][35][36].…”

Section: Ketogenic Dietmentioning

confidence: 99%

Comparative Effects of Calorie Restriction on Health Span and Insulin Resistance: Classic Calorie Restriction Diet vs Ketosis-Inducing Diet

Napoleão¹,

Fernandes²,

Miranda³

et al. 2021

Preprint

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As Chronic Non-Communicable Diseases (CNCD) increase, preventive approaches become more crucial. In this review, Calorie Restriction (CR) effects on human beings were evaluated, comparing benefits and risks of different CR diets: classic CR vs ketosis-inducing diets, including Intermittent Fasting (IF), Classic Ketogenic Diet (CKD), Fasting Mimicking Diet (FMD), Very-Low-Calorie Ketogenic Diet (VLCKD) and Spanish Ketogenic Mediterranean Diet (SKMD). Special emphasis on Insulin Resistance (IR) was placed, as it mediates Metabolic Syndrome (MS), a risk factor for CNCD, and predicts MS diagnosis. CR is the most robust intervention known to increase lifespan and health span, with high evidence and known biochemical mechanisms. CR improves cardiometabolic risk parameters, boosts exercise insulin sensitivity response, and there may be benefits of implementing moderate CR on healthy young and middle-aged individuals. However, there is insufficient evidence to support long-term CR. CKD is effective for weight and MS management, and may have additional benefits such as prevention of muscle loss and appetite control. SKMD has extreme significance benefits for all the metabolic parameters studied. Studies show inconsistent benefits of IF compared to classic CR. More studies are required to study biochemical parameters, reinforce evidence, identify risks, and seek effective and safe nutritional CR approaches.

show abstract

Dieta cetogênica e dieta de Atkins modificada no tratamento da epilepsia refratária em crianças e adultos

Cited by 7 publications

References 21 publications

Effects of Calorie Restriction on Health Span and Insulin Resistance: Classic Calorie Restriction Diet vs. Ketosis-Inducing Diet

Effects of Calorie Restriction on Health Span and Insulin Resistance: Classic Calorie Restriction Diet vs. Ketosis-Inducing Diet

A “Dieta Da Proteína” Reduz O Diâmetro E a Densidade Volumétrica Glomerular Em Ratas

Comparative Effects of Calorie Restriction on Health Span and Insulin Resistance: Classic Calorie Restriction Diet vs Ketosis-Inducing Diet

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