Sepse por Serratia marcescens KPC

Dissemination of bla KPC-2 by the Spread of Klebsiella pneumoniae Clonal Complex 258 Clones (ST258, ST11, ST437) and Plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae Species in Brazil

“…It also constitutes the first description of ST258 in Brazil associated with a nosocomial outbreak in a university hospital of Ribeirao Preto city. Although only sporadic cases of KPC producers have been documented in South America (Argentina, Colombia, and Brazil) (9,11,24,40), this work has pointed out the high diversity of available genetic platforms carrying bla KPC-2 . This might greatly amplify the dissemination of KPC genetic elements in this continent.…”

“…Expansion of clones and plasmids that have acquired Tn4401 seems to have fuelled the recent pandemic dissemination of bla KPC genes (8,15,20,21,34). To date, only sporadic cases of K. pneumoniae, Enterobacter cloacae, Serratia marcescens, and Escherichia coli KPC-2 producers have been documented in Brazil (6,9,11,19,23,28,35,40).…”

Strength In Bacterial Pseudomonas Aeruginosa Sample

“…[12] KPC, is often found in K. pneumoniae, has high potential to spread, is a bacterium with the ability to transfer genetic material and resistance genes. [13] Easy dissemination impedes the control of epidemics, and leaves on alert health professionals, such infections have extremely difficult to treat and raise the high mortality rates. Although it is common in Klebsiella pneumoniae, KPC and can be identified in other bacteria, such as: Enterobactercloacae, Citrobacterfreundii, Salmonella spp, E. coli Pseudomonasspp.…”

KPC-PRODUCING Serratia marcescens IN A HOME-CARE PATIENT FROM RECIFE, BRAZIL

“…marcescens isolates was reported by DEL PELOSO et al . 7 in intensive care unit (ICU) patients with urinary sepsis. Although the occurrence of bla KPC-2 in S. marcescens isolates has been described in nosocomial strains 4 , 16 , ICU patients may continue to be colonized by carbapenemase-producing isolates for long periods after hospital discharge, allowing its potential spread to households and the community 9 , 10 .…”