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Cited by 6 publications
(9 citation statements)
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“…In medicine, studies have shown that the presence of inflammation in some types of cancer is beneficial, as in melanomas (6). However, in mammary carcinomas (7) and in oral squamous cell carcinomas (8), the presence of chronic inflammation is considered an adjuvant of tumor growth tolerance.…”
Section: Research Articlementioning
confidence: 99%
“…In medicine, studies have shown that the presence of inflammation in some types of cancer is beneficial, as in melanomas (6). However, in mammary carcinomas (7) and in oral squamous cell carcinomas (8), the presence of chronic inflammation is considered an adjuvant of tumor growth tolerance.…”
Section: Research Articlementioning
confidence: 99%
“…The more specific markers for melanoma are melan--A (MART-1), HMB 45 and S-100 protein. Besides these, information about the aberrations of c-Kit gene in acral melanomas in mucosa or in areas of permanent sun exposure, are targeting therapeutic research, making these aberrations an important marker (10)(11)(12)(13)(14)(15). Immunohistochemistry performed in five cases for c-kit was positive in more than 50% of cells with good intensity in 4 cases and negative in one (case 5 with tumor in glans, pT1b).…”
Section: Discussionmentioning
confidence: 99%
“…As células maduras da base da lesão permeiam as fibras do tecido conectivo, formando filas indianas, o que difere do padrão fascicular de invasão do melanoma. (11) No ano de 1975, o grupo de Reed descreveu lesões que foram nomeadas de nevo de células fusiformes, ressaltando que lesões similares, descritas anteriormente, não tinham recebido reconhecimento clínico e patológico.…”
Section: Discussionunclassified
“…Pode-se encontrar infiltrado inflamatório variá-vel e vasodilatação local, assim como nos demais nevos, sendo os linfócitos e os plasmócitos os elementos mais frequentes (910,11) . O paciente também apresentava elastose e hialinização no tecido conjuntivo, correspondendo às alterações histopatológicas encontradas, caracteristicamente, no pterígio.…”
Section: Discussionunclassified