Saldanha LA. Efeitos da ingestão de cafeína, café (Coffea arabica) e chá-mate (Ilex paraguariensis) sobre a atividade lipolítica do tecido adiposo e parâmetros metabólicos em ratos submetidos ao exercício físico./Effects of the ingestion of caffeine, coffee (Coffea arabica) and roasted maté tea (Ilex paraguariensis) on the adipose tissue lipolytic activity and metabolic parameters on rats submitted to physical exercise [thesis]. São Paulo (BR): Faculdade de Saúde Pública USP; 2012. Introduction. The excess of body fat is associated with the development of chronic non-communicable diseases. Physical exercise enhance lipolysis. The mobilization of fatty acids (FA) is the first stage for the use of lipids as a source of energy by skeletal muscle. In order to increase the use of FA, substances have been used.Objective. This work compared the effects of caffeine, coffee and maté tea on the performance, metabolic parameters and lipolysis in response to acute physical exercise on a treadmill, in Wistar rats. Methods. The study was developed in stage 1 (exercise until exhaustion, n=15) and stage 2 (exercise lasting for 60 minutes, n=45).The design consisted of groups: control (C), control exercise (CE), caffeine exercise (CFNE), coffee exercise (CAFE) and maté tea exercise (CME). For stage 1, the performance, the differences in the total body mass and glucose (post-versus preexercise), and lipolytic activity were compared. For the stage 2, comparisons were made among the differences in the total body mass and glucose (post-versus preexercise), lipolytic activity, blood lactate level and muscular glycogen content. The data were presented as average ± standard error. The data were analyzed by means of general linear models and the deltas by the orthogonal contrasts technique. Pearson's 12 linear correlation was used to check the association between the variables of interest.
Results.In stage 1, no differences were observed between the groups in terms of performance. The post-exercise total body mass, when compared to the pre-exercise, decreased for the CE (188%), CFNE (273%), CAFE (319%) e CME (204%) groups, when compared to C. There was no difference for glucose (post-versus pre-exercise) between groups. An increase of 92% in lipolysis was observed in the CAFE group, when compared to C. In stage 2, there was a decrease in the post-exercise total body mass, when compared with pre-exercise, in the CE and CFNE (263%), CAFE (230%) and CME (183%) groups. An increase in post-exercise glucose, in comparison with the pre-exercise, was observed in groups CFNE (343% and 220%, when compared to C and CE, respectively) and CME (179%), when compared to C.Lipolysis increased for the CFNE and CAFE groups when compared to groups C (150% and 233%, respectively) and CE (51% and 101%, respectively). No significant differences were observed between the groups for the blood lactate and the muscular glycogen levels. It wasn't observed correlation between the different variables, for stage 1 and 2. Conclusion. Following exercise until exhaustion...