Seroprevalence of &lt;italic&gt;Borrelia burgdorferi&lt;/italic&gt; in occupationally exposed persons in the Belgrade area, Serbia

Jovanović, Dalibor; Atanasievska, Sonja; Protic-Djokic, Vesna; Rakic, Uros; Lukac-Radoncic, Elvira; Ristanović, Elizabeta

doi:10.1590/s1517-838246320140698

Cited by 21 publications

(20 citation statements)

References 40 publications

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“…The estimated Borrelia IgG seroprevalence ratio was similar to ratios obtained among blood donors in European countries such as Belgium (2·6%, urban blood donors; 2·9%, rural blood donors) (De Keukeleire et al ., ), Romania (4·3%) (Hristea et al ., ), central Italy (4·3%) (Santino et al ., ) and Austria (3·8%) (Pierer et al ., ). However, it was lower compared to other countries such as Serbia (8·6%) (Jovanovic et al ., ) and especially Tanzania, where the anti‐borrelia IgG prevalence was very high (30%) (Mhalu & Matre, ). This variability in the seroprevalence can be the result of different sensitivities of the applied test.…”

Section: Discussionmentioning

confidence: 99%

Serological evidence of Borrelia circulation among blood donors in the São Paulo state, Brazil

Slavov

Christova

Ferreira

et al. 2019

Transfusion Medicine

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SUMMARY Objective The objective of this study was to examine the Borrelia seroprevalence among blood donors in Southeast Brazil. Background There is evidence that Borrelia spirochetes are circulating in Brazil; however, there are no studies that characterise these bacteria and investigate their seroprevalence in the Brazilian population. Such a situation, combined with a recent outbreak of tick‐borne Rocky Mountain spotted fever in the São Paulo state demonstrates the increasing role of ticks as arthropod vectors in Brazil. Methods For the purpose of the study, 452 blood donors from Ribeirão Preto city, São Paulo state were tested using anti‐Borrelia immunoglobulin G (IgG) assay. The positive results were also confirmed by Western blot for anti‐borrelia IgM/IgG. Results The anti‐Borrelia IgG enzyme‐linked immunosorbent assay (ELISA) showed nine positive and nine borderline reactive samples, giving a total seroprevalence of 2·0% of anti‐Borrelia IgG among Brazilian blood donors. The confirmation of the seropositive and borderline samples by Borrelia Western blot was demonstrated by IgG‐positive results in 16 samples (a seroprevalence of 3.5%). Anti‐Borrelia IgM antibodies were also detected in one sample. Conclusions Our results demonstrate that Borrelia‐like spirochetes may be circulating among blood donors from the São Paulo State and that the ticks have an important epidemiological role as vectors of bacterial infections in this Brazilian region. These results not only alert us to possible actions that might be undertaken in order to completely characterise the aetiological agents of Lyme‐like syndromes in Brazil but also the possible impact that these bacterial agents might have on haemotherapy practices.

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Section: Discussionmentioning

confidence: 99%

Serological evidence of Borrelia circulation among blood donors in the São Paulo state, Brazil

Slavov

Christova

Ferreira

et al. 2019

Transfusion Medicine

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“…artritis, upalu zglobova, kao i oštećenja perifernog nervnog sistema. U Srbiji godišnje oboli oko 400 osoba od Lajmske bolesti (2). U Beogradu u proseku svaki dan 30 osoba prijavi ujed krpelja (2).…”

Section: Uvodunclassified

“…U Srbiji godišnje oboli oko 400 osoba od Lajmske bolesti (2). U Beogradu u proseku svaki dan 30 osoba prijavi ujed krpelja (2). Samo komarci prenose više infektivnih bolesti na ljude i životinje od krpelja.…”

Section: Uvodunclassified

Demographic aspects of tick bites in Belgrade: Two-year retrospective study

Zelenović¹,

Minić²

2018

Medicinski podmladak

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Introduction: Ticks are becoming an increasing problem in Europe. Every outing in nature bares a risk of a tick bite, especially in the spring and summer. Ticks are spiderlike ectoparasites from the Ixodida family, subclass Acarina. They may induce an irritation, trigger abscess and carry numerous spirohets, most commonly the bacteria Borrelia burgdorferi which can cause Lyme disease. The goal of this study was to determine the distribution of tick bites in studied population according to: bite localization, time (according to months) and Belgrade municipaliteies where the bite occurred. Materials and methods: 1199 individuals participated in this retrospective study, who were being treated at Dermatovenerology Clinic KCS Belgrade between January 2014 and December 2015, for tick bites. Following data was gathered: demographic data, geographical data about the place where the bite occurred, time of year, as well as the part of the body that was influenced. Results: In the year 2014, 600 (50 %) patients were treated, whereas in 2015 599 (50 %) patients were treated. There were 715 (59.7 %) males and 483 (40.3 %) females. The average age of the participants was 41 (1-87). Most of the participants had one bite, 1128 (94.1 %), 19 (1.6 %) participants had two bites, while 6 (0.5 %) participants had more than two bites. Most of the bites occurred during spring months 989 (82.5 %), in the municipalities of Vozdovac 244 (20.4 %) and Cukarica 224 (18.7 %). The most common bite sites were below the waist line in all participant groups except for children, who had bites in the head and neck region. Conclusion: Exposure to ticks carries a risk of getting Lyme disease. Whether or not the tick may be infected, it is suggested to take it out as soon as possible, so that it would not feast on blood and influence Lyme disease.

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“…During the next two decades, 16 borrelia strains were isolated from I. ricinus ticks in different studies; all were characterized either as B. burgdorferi s.s. or B. afzelii by molecular methods (Jovičić et al 2003;Ristanović et al 2007;Čekanac et al 2010;Potkonjak et al 2014). The available data on the epidemiology and clinical manifestation of LB in Serbia are scarce and mainly based on seroprevalence surveys (Savić et al 2010;Jovanović et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Diversity of Lyme borreliosis spirochetes isolated from ticks in Serbia

Ćakić

Veinović

Cerar

et al. 2019

Medical Vet Entomology

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Spirochetes from the Borrelia burgdorferi sensu lato (s.l.). (Spirochaetales: Spirochaetaceae) species complex, including the causative agents of Lyme borreliosis, have been isolated from ticks, vertebrate reservoirs and humans. Previous analyses based on direct molecular detection in ticks indicated a considerable diversity of B. burgdorferi s.l. complex in Serbia. The present study aimed (a) to isolate borrelia strains from Serbia; (b) to determine their genotypic characteristics; and (c) to establish a collection of viable B. burgdorferi s.l. strains for further biological, ecological and genetic studies. For the present study, 231 adult Ixodes ricinus (Ixodida: Ixodidae) ticks from 16 ecologically different localities in Serbia were individually processed to cultivate B. burgdorferi s.l. This led to the isolation of 36 strains. A hbb gene quantitative real‐time polymerase chain reaction (PCR) based on melting temperature determination and ospA gene sequencing were used to genotype the isolated spirochetes. The species identified based on the hbb gene real‐time PCR were: Borrelia lusitaniae (44.4%), Borrelia afzelii (36.1%), Borrelia garinii (13.9%) and Borrelia valaisiana (5.6%), whereas the ospA sequence analysis revealed the occurrence of Borrelia bavariensis. This is the first report of the isolation of B. lusitaniae, B. garinii, B. bavariensis and B. valaisiana strains in Serbia.

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Seroprevalence of <italic>Borrelia burgdorferi</italic> in occupationally exposed persons in the Belgrade area, Serbia

Cited by 21 publications

References 40 publications

Serological evidence of Borrelia circulation among blood donors in the São Paulo state, Brazil

Serological evidence of Borrelia circulation among blood donors in the São Paulo state, Brazil

Demographic aspects of tick bites in Belgrade: Two-year retrospective study

Diversity of Lyme borreliosis spirochetes isolated from ticks in Serbia

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