volume 43, issue 1, P235-242 2012
DOI: 10.1590/s1517-83822012000100026
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Fernanda Gomes, Bruna Leite, Pilar Teixeira, Joana Azeredo, Rosário Oliveira

Abstract: ABSTRACTStaphylococcus epidermidis is the most frequent cause of nosocomial sepsis and catheter-related infections, in which biofilm formation is considered to be the main virulence mechanism. In biofilm environment, microbes exhibit enhanced resistance to antimicrobial agents. This fact boosted the search of possible alternatives to antibiotics. Farnesol and N-acetylcysteine (NAC) are non-antibiotic drugs that have demonstrated antibacterial properties. In this study, the effect of farnesol and NAC isolated …

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