Trichosporon pullulans (Lidner) Diddens & Lodder isolated from the oral cavity of AIDS patient

Abstract

Trichosporon has been reported as a remarkable emerging pathogen and usually occurs in imunodrepressed patients. An oropharyngeal secretion sample was collected from a patient with AIDS, at the Sector of Infectious and Parasitic Diseases, Osvaldo Cruz University Hospital, Pernambuco State, Brazil. No yeast cells or arthroconidia were observed in the direct exam, but a culture was positive for Trichosporon pullulans, which is being reported in an AIDS patient for the first time. Key words: Trichosporon pullulans, AIDS.The importance of the study of fungi as pathogenic agents from the oral cavity has been reported, indicating the mouth as an entrance of many mycosis etiological agents (11,14,15). Trichosporon is found in the indigenous mycobiota of the skin surface, mainly in the genito crural and perianal areas of homosexuals (17).Hematogenic dissemination due to Trichosporon species is frequently observed in patients with low immunity, particularly in cases of neutropenia or leukemia (6,10,16). Among the species connected to mycosis, T. pullulans is recognized as usually occurring in imunodepressed individuals (2,6,8,9,12).This study reports the isolation of T. pullulans from a clinical sample of an AIDS patient, hospitalized in the Sector of Infectious and Parasitic Diseases, University Hospital Osvaldo Cruz, Pernambuco State University, Recife, Pernambuco.The patient is a 35-years-old male (C.J.V.), living as a mason in Paulista (Recife Metropolitan Region -Pernambuco State, Brazil), and presented lesions in the oral cavity and underside of the tongue. The sample of oropharyngeal secretion was collected with a sterilized swab that was placed into a tube containing 2mL of sterile destilled water plus 50 mg of * Corresponding author. Mailing address: Av. Boa Viagem, 3376/92,

Molecular Identification and Susceptibility ofTrichosporonSpecies Isolated from Clinical Specimens in Qatar: Isolation ofTrichosporon dohaenseTaj-Aldeen, Meis & Boekhout sp. nov

“…Cases of Guehomyces pullulans (T. pullulans) (17) infection of patients with chronic granulomatous disease (45) or the isolation of this species from the oral cavities of AIDS patients (52) (67). T. asahii is isolated mainly from the blood, lung tissue, and urine of patients suffering from deep-seated trichosporonosis (23,67), but it is also isolated from skin (23) or white piedra (14,78).…”

Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies

“…(2) reported a systemic infection involving T. cutaneum in a child with Wilm’s tumour and Neves et al . (9) isolated T. pulullans from the oral cavity of an HIV positive patient.…”

Genetic diversity and antifungal susceptibility testing of Trichosporon asahii isolated of Intensive Care Units patients

“…Recently, a case was reported of systemic Trichosporon cutaneum infection in a 3-year-old infant with Wilms' tumor (5). In the same hospital, an oropharyngeal secretion sample was collected from an AIDS patient with oral lesions and Trichosporon pullulans was isolated (34).…”

“…In Brazil there are few survey on these yeasts (30,34,43). In this study we examined the genetic diversity and biochemical characteristics of T.asahii strains recovered from clinical specimens (oral cavity and urine) from patients in Intensive Care Units (ICU), as well as the correlation between the drug susceptibility profile and genetic changes detected by RAPD (primer M13 and 6).…”