Excreção de gordura fecal de ratos (Rattus norvegicus, Wistar), submetidos a dietas hiperlipídicas e hipercolesterolêmicas suplementadas com quitosana

Cherem, Adriana da Rosa; Bramosrki, Adriana

doi:10.1590/s1516-93322008000400017

Cited by 6 publications

(6 citation statements)

References 18 publications

(28 reference statements)

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“…Contrary to the expectations, there was no difference in weight gain between the groups, finding that was also observed by Cherem and Bramosrki (2008). This is probably due to the reduced food intake and digestibility of hyperlipidemic diets, which contributed to reduce the amount of energy absorbed.…”

Section: Discussioncontrasting

confidence: 84%

Antioxidant potential of barley extract in rats subjected to a high-fat diet

Zimmermann¹,

Rivero²,

Bezerra³

et al. 2013

Food Sci. Technol

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Antioxidants have the ability to neutralize free radicals produced in the body during lipid oxidation. The objective in this article was to study the effect of the barley extract on lipid oxidation in rats subjected to a high-fat diet. The experiment lasted 67 days. The animals were separated into three experimental groups: standard (P), high-fat diet group (L), and group with high-fat diet supplemented with barley extract (C). The feed intake of L and C groups was the lowest (p < 0.05). The treatments did not influence weight gain, organ weight, and the blood parameters measured. However, the levels of malondialdehyde present in the liver tissue were higher in the L group and lower in the P and C groups. Therefore, the results indicated an increased level of lipid peroxidation in the liver of rats subjected to high-fat diet, which was reduced by the consumption of barley.

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Section: Discussioncontrasting

confidence: 84%

Antioxidant potential of barley extract in rats subjected to a high-fat diet

Zimmermann¹,

Rivero²,

Bezerra³

et al. 2013

Food Sci. Technol

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show abstract

“…The increased excretion of fecal fat may be related to the high content of soluble dietary fiber present in the food testing. Soluble fiber slows digestion and absorption of fat, thereby increasing its excretion in the feces (Cherem & Bramosrki, 2008). Moreover, Marques et al (2015) in an in vitro study showed that caupi bean peptides were able to inhibit the HMG-CoA reductase and reduce the micellar solubilization of cholesterol, thereby increasing the fecal excretion of lipids.…”

Section: Discussionmentioning

confidence: 99%

Staple food crops from Brazilian Biofortification Program have high protein quality and hypoglycemic action in Wistar rats

et al. 2020

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Biofortified staple food crops have become an effective tool by which to address micronutrient deficiencies in many at-risk populations. The effect of these food crops on the micronutrient status has been evaluated, however there is no studies investigating their protein quality, neither by themselves or in a food combination. Thus, this study investigated the effect of combinations of beans and rice, target for biofortification, with high carotenoids content crops (sweet potato and pumpkin) on protein quality, intestinal function and glycemia. Eight groups were evaluated (n=6): 1) rice + Caupi bean (RCB); 2) rice + Pontal bean (RPB); 3) rice + Caupi bean + pumpkin (RCBP); 4) rice + Pontal bean + pumpkin (RPBP); 5) rice + Caupi bean + sweet potato (RCBS); 6) rice + Pontal bean + sweet potato (RPBS); 7) casein (positive control); and 8) nitrogen free (negative control). Tested groups showed high protein quality, and groups containing Caupi bean showed higher true digestibility. Groups containing Pontal bean had a greater reduction of blood glucose compared to casein. Tested groups showed higher fecal excretion of lipids. Combination of food target for biofortification showed high protein quality, and the combinations containing Pontal beans showed hypoglycemic effect.Practical Application: The Biofortification program not only provide an additional amount of micronutrient but also contribute to the protein intake of the risk population and potentially improve the glycemic status and intestinal function. Thus, the utilization of these foods may have a positive impact on the nutritional status and health of population at risk for micronutrient deficiency. Dias et al.

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“…Em sua pesquisa, Geremias R (11) verificou que os ra-tos suplementados com 5% (m/m) de quitosana apresentaram redução em sua massa corporal quando comparados com o controle e hiperlipídico. Diferente de Cherem & Bramorski (14) que, em sua pesquisa, não observaram diferenças na redução da massa corporal de ratos suplementados com quitosana e os grupos controle. Entretanto, Trautwein E, et al (15) verificaram que hamsters que consumiram dietas com 8% (m/m) de quitosana tiveram sua massa corporal diminuída significativamente; no entanto, ao utilizar suplementação de 4% (m/m) de quitosana, a diminuição da massa corporal não foi tão efetiva.…”

Section: Discussionunclassified

“…Os ratos que receberam suplementação com quitosana (CQ e HQ) aumentaram o seu consumo alimentar ao serem comparados com seus controles. O mesmo pode ser observado em estudo realizado por Cherem & Bramorski (14) ao adicionar à dieta hipercalórica de ratos Wistar 5% (m/m) de quitosana de duas diferentes marcas comerciais; os grupos com suplementação da fibra ingeriram uma maior quantidade de ração quando comparado a seus controles. Também, em seus estudos, Gallaher CM e Azuma K, et al (10,16) observaram maior ingestão alimentar nos grupos com suplementação de quitosana.…”

Section: Discussionunclassified