Sperm Quality and Testicular Histomorphometry of Wistar Rats Supplemented with Extract and Fractions of Fruit of Tribulus terrestris L.

Oliveira, Nelma Neylanne Pinho Muniz; Félix, Matheus Augusto Rodrigues; Pereira, Tauany Costa Silva; Rocha, Luiz Célio Souza; Miranda, José Romilson Paes de; Zangerônimo, Márcio Gilberto; Pinto, José Eduardo Brasil Pereira; Bertolucci, Suzan Kelly Vilela; Sousa, Raimundo Vicente de

doi:10.1590/s1516-89132015060278

Cited by 20 publications

(14 citation statements)

References 24 publications

(23 reference statements)

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“…The average score of 50 tubules was used to determine the spermatogenic activities (Erdemir et al, 2014). The germinal epithelial height and the average diameter of the seminiferous tubules and its luminal diameter were taken according to the method described by Oliveira et al (2015).…”

Section: Histological Studiesmentioning

confidence: 99%

Warfarin‐induced vitamin K deficiency affects spermatogenesis in Sprague‐Dawley rats

et al. 2019

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Vitamin K is present in the testes though its actual function in male reproduction is poorly understood. This study investigated the harmful effect of extrahepatic vitamin K insufficiency on the testicular structure. Sprague-Dawley rats were fed with a diet containing warfarin for 2, 4 and 8 weeks; control animals received a standard diet without warfarin. It was found that extrahepatic vitamin K deficiency that is induced by warfarin results in histopathological features that range from delayed spermiation, presence of multinucleated giant cells in the seminiferous tubules, germ cells degeneration, asthenozoospermia, oligozoospermia and increase in the percentage of abnormal sperm morphology when compared to the controls. Data obtained from the two groups were analysed using the Student t test. It is concluded that warfarin-induced vitamin K deficiency has a negative impact on spermatogenesis. K E Y W O R D Smale infertility, multinucleated giant cells, testes, vitamin K, warfarin

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Section: Histological Studiesmentioning

confidence: 99%

Warfarin‐induced vitamin K deficiency affects spermatogenesis in Sprague‐Dawley rats

et al. 2019

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“…The hexanic and aqueous soluble fraction in the methanol fractions promoted changes in the intertubular compartment because they increased the nuclear volume, cytoplasmic volume and individual volume of Leydig cells in male Wistar rats [57]. …”

Section: Pharmacological Activitiesmentioning

confidence: 99%

“…In the literature, it has been concluded that the ethanol extract of T. terrestris (EETT) influences spermatogenesis, as shown by the evident changes in the tubular compartment of the testes, such as increases in the total tube length, tubular volume and height of the seminiferous epithelium. The hexanic and aqueous soluble fraction in the methanol fractions promoted changes in the intertubular compartment because they increased the nuclear volume, cytoplasmic volume and individual volume of Leydig cells in male Wistar rats [ 57 ].…”

Section: Pharmacological Activitiesmentioning

confidence: 99%

A review of traditional pharmacological uses, phytochemistry, and pharmacological activities of Tribulus terrestris

Zhu

Meng

et al. 2017

Chemistry Central Journal

129

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Tribulus terrestris L. (TT) is an annual plant of the family Zygophyllaceae that has been used for generations to energize, vitalize, and improve sexual function and physical performance in men. The fruits and roots of TT have been used as a folk medicine for thousands of years in China, India, Sudan, and Pakistan. Numerous bioactive phytochemicals, such as saponins and flavonoids, have been isolated and identified from TT that are responsible alone or in combination for various pharmacological activities. This review provides a comprehensive overview of the traditional applications, phytochemistry, pharmacology and overuse of TT and provides evidence for better medicinal usage of TT.

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“…Os resultados demonstraram que o extrato etanólico de T. terrestris (EETT) influencia a espermatogênese pelas evidentes alterações no compartimento tubular dos testículos, como aumentos no comprimento total do tubo, volume tubular e altura de o epitélio seminífero. A fração solúvel hexânica e aquosa nas frações de metanol promoveram alterações no compartimento intertubular, pois aumentaram o volume nuclear, o volume citoplasmático e o volume individual das células de Leydig em ratos Wistar machos (Oliveira et al, 2015).…”

Section: Habituais Usos Farmacológicos Do Tribulus Terrestrisunclassified

Plantas Que Agem No Sistema Nervoso Central: O Uso Dos Fitoterápicos Kava Kava, Passiflora E Valeriana No Tratamento De Transtorno De Ansiedade

Araujo¹,

Santos²,

Fernandes³

et al. 2021

Farmácia Na Atenção E Assistência À Saúde 4

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Direitos para esta edição cedidos à Atena Editora pelos autores. Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica. A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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Sperm Quality and Testicular Histomorphometry of Wistar Rats Supplemented with Extract and Fractions of Fruit of Tribulus terrestris L.

Abstract: ABSTRACT

Cited by 20 publications

References 24 publications

Warfarin‐induced vitamin K deficiency affects spermatogenesis in Sprague‐Dawley rats

Warfarin‐induced vitamin K deficiency affects spermatogenesis in Sprague‐Dawley rats

A review of traditional pharmacological uses, phytochemistry, and pharmacological activities of Tribulus terrestris

Plantas Que Agem No Sistema Nervoso Central: O Uso Dos Fitoterápicos Kava Kava, Passiflora E Valeriana No Tratamento De Transtorno De Ansiedade

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