Supercritical CO2 extraction of Schinus molle L with co-solvents: mathematical modeling and antimicrobial applications

Scopel, Rodrigo; Neto, Roberto Góes; Falcão, Manuel; Cassel, Eduardo; Vargas, Rubem Mário Figueiró

doi:10.1590/s1516-89132013000300020

Cited by 20 publications

(12 citation statements)

References 13 publications

(16 reference statements)

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“…terebinthifolius leaves essential oil low content does not correspond to those ones presented in the literature (Barbosa et al, 2007;Santos et al, 2009). Moreover, S. terebinthifolius fruit essential oil content (Gomes et al, 2013a) and S. molle leaves and fruit essential oils were similar to those ones presented in the literature (Dikshit et al, 1986;Zahed et al, 2010;Torres et al, 2012;Scopel et al, 2013) and higher to those ones presented by Santos et al (2009).…”

Section: Resultsmentioning

confidence: 50%

Volatiles composition and extraction kinetics from Schinus terebinthifolius and Schinus molle leaves and fruit

Cavalcanti

Alves

Silva

et al. 2015

Revista Brasileira de Farmacognosia

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Section: Resultsmentioning

confidence: 50%

Volatiles composition and extraction kinetics from Schinus terebinthifolius and Schinus molle leaves and fruit

Cavalcanti

Alves

Silva

et al. 2015

Revista Brasileira de Farmacognosia

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“…Different results have been reported regarding the content of essential oil extracted from S. molle , using different methods, such as supercritical fluid extraction (Barroso et al 2011; Scopel et al . 2013), extraction from fresh plant parts (Murray et al . 2005; Benzi et al .…”

Section: Discussionmentioning

confidence: 99%

In vitro efficacy of essential oils and extracts of Schinus molle L. against Ctenocephalides felis felis.

et al. 2016

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Extracts and essential oils from plants are important natural sources of pesticides. These compounds are considered an alternative to control ectoparasites of veterinary importance. Schinus molle, an endemic species of Brazil, produces a high level of essential oil and several other compounds. The aim of this work was to determinate the chemical composition of extracts and essential oils of S. molle and further to evaluate the activity against eggs and adults of Ctenocephalides felis felis, a predominant flea that infests dogs and cats in Brazil. In an in vitro assay, the non-polar (n-hexane) extract showed 100% efficacy (800 µg cm(-2); LD50 = 524·80 µg cm(-2)) at 24 and 48 h. Its major compound was lupenone (50·25%). Essential oils from fruits and leaves were evaluated, and had 100% efficacy against adult fleas at 800 µg cm(-2) (LD50 = 353·95 µg cm(-2)) and at 50 µg cm(-2) (LD50 = 12·02 µg cm(-2)), respectively. On the other hand, the essential oil from fruits and leaves was not active against flea eggs. This is the first study that reports the insecticidal effects of essential oils and extracts obtained from Schinus molle against Ctenocephalides felis felis.

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“…The extraction process was carried out in a pilot plant described in detail in previous works [74,75]. All experiments were conducted in the 500 mL vessels loaded with 80 g of A. mearnsii dried flowers.…”

Section: Supercritical Fluid Extraction (Sfe)mentioning

confidence: 99%

The Response Surface Optimization of Supercritical CO2 Modified with Ethanol Extraction of p-Anisic Acid from Acacia mearnsii Flowers and Mathematical Modeling of the Mass Transfer

Silva¹,

Júnior²,

Almeida³

et al. 2022

Molecules

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A widely disseminated native species from Australia, Acacia mearnsii, which is mainly cultivated in Brazil and South Africa, represents a rich source of natural tannins used in the tanning process. Many flowers of the Acacia species are used as sources of compounds of interest for the cosmetic industry, such as phenolic compounds. In this study, supercritical fluid extraction was used to obtain non-volatile compounds from A. mearnsii flowers for the first time. The extract showed antimicrobial activity and the presence of p-anisic acid, a substance with industrial and pharmaceutical applications. The fractionation of the extract was performed using a chromatographic column and the fraction containing p-anisic acid presented better minimum inhibitory concentration (MIC) results than the crude extract. Thus, the extraction process was optimized to maximize the p-anisic acid extraction. The response surface methodology and the Box–Behnken design was used to evaluate the pressure, temperature, the cosolvent, and the influence of the particle size on the extraction process. After the optimization process, the p-anisic acid yield was 2.51% w/w and the extraction curve was plotted as a function of time. The simulation of the extraction process was performed using the three models available in the literature.

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Supercritical CO2 extraction of Schinus molle L with co-solvents: mathematical modeling and antimicrobial applications

Cited by 20 publications

References 13 publications

Volatiles composition and extraction kinetics from Schinus terebinthifolius and Schinus molle leaves and fruit

Volatiles composition and extraction kinetics from Schinus terebinthifolius and Schinus molle leaves and fruit

In vitro efficacy of essential oils and extracts of Schinus molle L. against Ctenocephalides felis felis.

The Response Surface Optimization of Supercritical CO2 Modified with Ethanol Extraction of p-Anisic Acid from Acacia mearnsii Flowers and Mathematical Modeling of the Mass Transfer

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