Development and optimization of extractives from Astronium urundeuva (allemão) Engl. by factorial design

Abstract

The purpose of this study was to evaluate the influences from variables of preparation on dry residue and total tannins from macerates of Astronium urundeuva barks. Thus, a 3 2 factorial design was used to study the importance of plant proportion (10, 15 and 20 %, w/v) and the ethanol concentration (40, 60 and 80 %, v/v)

Nanostructured lipid system as a strategy to improve the anti-Candida albicans activity of Astronium sp.

“…Among these species, A. urundeuva is the most well-known due to its biological properties as some studies have described the presence of important components, including flavonoids, essential oils, and hydrolyzable and condensed tannins. 10 Some of the antiulcer effects of aqueous and alcoholic extracts of plants from the Astronium genus against experimental ulcers were observed in rats. More recently, other studies have shown antioxidant, antidiarrheal, anti-inflammatory, and analgesic effects.…”

Optimization of Condensed Tannin Aqueous Extraction from Cashew Tree Pruning Residue Using Response Surface Methodology and Its Drying

“…On the other hand, the quadratic effect of L/S ratio was significant and negative ( Table 4). The contribution of the quadratic term is interpreted as the presence of a curve and represents the nature of the response surface system (maximum, minimum, or saddle point) [23]. Hence, the negative signal for the quadratic term reveals a convex curve, as was observed for the L/S ratio variable (Fig.…”

EXTRACTION OF MONOMERS OF HYDROLYSABLE TANNINS FROM PODS OF Libidibia ferrea (Mart. ex Tul.) L. P. QUEIROZ: EFFECTS OF SOLVENT AND AMOUNT OF DRUG USING RESPONSE-SURFACE METHODOLOGY AND DESIRABILITY PROFILE

“…The quadratic term demonstrates the contribution of the factor to the presence of curvature, which can be observed in the response surface graphs, indicating the nature of the system for maximum and minimum values under optimal conditions. 11,17 The study of RSMs generated by quadratic models reveals critical points of the experimental field that can characterize the nature of the surface system (maximum, minimum or saddle). The behavior is result of the contributions of the second order terms and describes the presence of curvatures.…”

“…The extractive efficiency (EE) was determined by the relation of the contents of the metabolites of interest (polyphenol, gallic acid or ellagic acid) to the solid content (dry residue) obtained for the extracts, according to the equation below. 11…”

“…Thus, it is important to evaluate extractive methods, solvents, drug proportion, as well as the influence on the marker content and the physicochemical properties of the extractive solutions to ensure reproducibility and quality of the obtained products. [11][12][13][14][15] These effects can be measured through factorial assays, which allow the evaluation of two or more factors, also allowing the measurement of joint effects, determining possible compatibilities and incompatibilities. 16,17 The effect of extraction parameters, such as solvent and amount of drug on dry residue, total polyphenol content (TPC) and content of markers from Libidibia ferrea pods has not been studied and will therefore be evaluated in the present work, using Response Surface Methodology and Desirability profile, in order to maximize the extraction of chemical markers important for the biological activities from pods of L. ferrea.…”