Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity

Presibella, Mayra Marinho; Villas-Bôas, Larissa De Biaggi; Belletti, Klezia Morais da Silva; Santos, Cid Aimbiré de Moraes; Weffort-Santos, Almeriane Maria

doi:10.1590/s1516-89132006000600005

Cited by 38 publications

(27 citation statements)

References 25 publications

(32 reference statements)

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“…Some identified constituents in this species have been also reported in A. conyzoides (Okunade, 2002;Nébié et al 2004), Chamomilla recutita (Presibella et al, 2006) and Rosmarinus officinalis (Atti-Santos et al, 2005). Results observed in this study showed this to be the first report describing the antinociceptive and anti-inflammatory activities from A. fastigiatum.…”

Section: Discussionsupporting

confidence: 73%

Analgesic and anti-inflammatory properties of essential oil from Ageratum fastigiatum

Del-Vechio-Vieira

Sousa

Miranda

et al. 2009

Braz. arch. biol. technol.

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The chemical composition, analgesic and anti-inflammatory properties of essential oil from Ageratum fastigiatumwere investigated. The main compounds found in the essential oil were germacrene D, α-humulene and β-cedrene. The oil, with LD 50 of 2.50 g/kg, inhibited the acetic acid-induced writhing at the dose of 200 mg/kg. In the formalin test, the oil inhibited the first phase (200 mg/kg) and the second phase (100 mg/kg and 200 mg/kg). In the hot plate test, after 30 and 60 min of treatment the doses of 100 and

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Section: Discussionsupporting

confidence: 73%

Analgesic and anti-inflammatory properties of essential oil from Ageratum fastigiatum

Del-Vechio-Vieira

Sousa

Miranda

et al. 2009

Braz. arch. biol. technol.

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“…O ensaio de quimiotaxia como proposto por Boyden no início dos anos 60 (Boyden, 1962) e suas variações tem se mostrado útil como uma metodologia in vitro para se investigar o efeito de extratos (Hofbauer et al, 2001;Ihantola-Vormisto et al, 1997;Presibella et al, 2007;Presibella et al, 2006) e de substâncias extraídas de plantas (Chen et al, 2001;Hofbauer et al, 1999;Muller et al, 1999) sobre a quimiotaxia de leucócitos. Neste trabalho, investigou-se o potencial do extrato de A. glabra e de seu ácido caurenóico no recrutamento de GNC de sangue periférico utilizando-se câmaras de Boyden.…”

Section: Discussionunclassified

“…Fotomicrografias foram obtidas com auxílio do programa Image Pro Plus, versão 3.0.01.00 para Windows. Os ensaios de quimiotaxia foram realizados em câmaras de Boyden de acordo com o protocolo experimental descrito por Presibella et al (2006). Os resultados estão expressos como a porcentagem média ± um erro padrão da média (EPM) de células recuperadas do compartimento inferior das câmaras em relação aos resultados obtidos para a caseína, usada como controle positivo de migração.…”

Section: Citocentrifugadosunclassified

“…Ainda, investigar simultaneamente o comportamento do ácido caurenóico dele purificado, uma vez que o mesmo tem sido alvo de estudos de modificações estruturais no esqueleto caurânico com o objetivo de se obter substâncias bioativas (Garcia et al, 2007). Machado-Jr. et al (2006) e Presibella (2006). Citocentrifugados preparados das frações de MNC utilizadas demonstraram a presença de 80-95% de linfócitos e 5-20% de monócitos.…”

Section: Introductionunclassified

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Potencial antiinflamatório de Annona glabra, Annonaceae

Siebra¹,

Nardin²,

Florão³

et al. 2009

Rev. bras. farmacogn.

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RESUMO:Annona glabra Linneau, Annonaceae, é uma árvore de pequeno porte encontrada em todo território brasileiro, principalmente nas áreas costeiras e conhecida popularmente como araticum-do-brejo e araticum-bravo. Este trabalho teve como objetivos investigar os efeitos do extrato de A. glabra e do ácido caurenóico dele purificado sobre a migração de granulócitos humanos e seu potencial imunomodulatório. Os resultados demonstraram que o extrato de A. glabra inibe a migração natural de granulócitos, de acordo com a dose, sugerindo potencial antiinflamatório, enquanto o ácido caurenóico demonstrou estimulá-la de forma significativa. Em contraste, nenhum efeito foi observado com relação a imunomodulação. Os efeitos apresentados ainda não foram descritos e, dessa forma, contribuem para ampliar a lista de atividades biológicas descritas não só do extrato de A. glabra, como também para o ácido caurenóico.Unitermos: Annona glabra, Annonaceae, ácido caurenóico, leucócitos humanos, quimiotaxia, imunomodulação.ABSTRACT: "Anti-inflammatory potential of Annona glabra, Annonaceae". Annona glabra Linneau, Annonaceae, is a small tree that grows over the Brazilian territory particularly in its coast, and is known as "araticum-do-brejo" and "araticum-bravo". The aim of this study was to evaluate the effects of the extract of A. glabra and its purified kaurenoic acid on the locomotion of human granulocytes and their immunomodulatory potential. The results herein presented showed a dose-dependent inhibition of the granulocyte migration for the extract, suggesting an anti-inflammatory activity, in contrast with a striking stimulation observed for the kaurenoic acid. When focusing immunomodulation properties, no activity could be drawn. The effects presented in this work are reported for the first time and extend the list of biological activities already described for the A. glabra extract as well as for the kaurenoic acid.

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“…The compositions of essential oil were compared in Egyptian and Brazilian chamomile ecotypes. The essential oil percent was reported from 0.2% to 0.3% in Brazilian ecotypes and it was also reported at 0.5% in Egyptian chamomile ecotypes [51]. Rowshan and Bahmanzadegan (2013) reported that the the application of exogenous salicylic acid with 200 and 400 mg¨L´1 concentrations may modify secondary metabolites and their pathway by impacts on plastids, the chlorophyll level and representing stress conditions.…”

Section: Essential Oil Contentmentioning

confidence: 98%

The Evaluation of Exogenous Application of Salicylic Acid on Physiological Characteristics, Proline and Essential Oil Content of Chamomile (Matricaria chamomilla L.) under Normal and Heat Stress Conditions

et al. 2016

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Abstract:The objective of this study was to investigate the effect of exogenous application of salicylic acid concentrations on the physiological and biochemical traits and essential oil content of chamomile under normal and heat stress conditions as induced by delayed sowing. The experiments were conducted during 2011-2012 as a factorial using a randomized complete block design with three replications, in a very hot region. The factors included five salicylic acid concentrations (0 (control), 1, 10, 25 and 100 mg¨L´1) and three chamomile cultivars (Bushehr, Bona, Bodegold). The seeds of chamomile were sown on two different sowing dates including an optimum planting date and a late planting date. The physiological traits (plant height, capitol diameter, 1000 grain weight, fresh and dried flower weight), total chlorophyll, proline and essential oil content were investigated. Analysis of variance showed that the effect of the environmental conditions (normal and heat stress) was significant on all physiological and biochemical traits with the exception of the essential oil content. The heat stress decreased physiological traits and total chlorophyll in comparison with the normal conditions but it had no significant effect on the essential oil content. Findings indicated that the application of exogenous salicylic acid improves essential oil content in chamomile cultivars under environmental heat stress conditions.

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Comparison of chemical constituents of Chamomilla recutita (L.) rauschert essential oil and its anti-chemotactic activity

Abstract: Several essential oil samples from dried flower-heads of

Cited by 38 publications

References 25 publications

Analgesic and anti-inflammatory properties of essential oil from Ageratum fastigiatum

Analgesic and anti-inflammatory properties of essential oil from Ageratum fastigiatum

Potencial antiinflamatório de Annona glabra, Annonaceae

The Evaluation of Exogenous Application of Salicylic Acid on Physiological Characteristics, Proline and Essential Oil Content of Chamomile (Matricaria chamomilla L.) under Normal and Heat Stress Conditions

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