2001
DOI: 10.1590/s1516-84842001000100007
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Abstract: 600 x 10(9)/L) this disease also exhibits accentuated hyperplasia of the megakaryocytes in the bone marrow, splenomegaly and clinically both thrombotic and haemorrhagic episodes. The etiology of this illness is largely unknown and the clinical manifestations are mostly asymptomatic, thus the diagnostic is often accidentally made. Here the case report of a 71-year-old male patient is discussed, who was admitted into hospital due to occlusion of the femoral artery requiring re-vascularisation. The physical exam … Show more

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Cited by 3 publications
(4 citation statements)
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“…Additionally, false thrombocytosis may occur associated with the presence of cytoplasmic fragments of nucleated cells and erythrocytes, lipemia, bacteria, or cryoglobulins (10) . In humans, primary or essential thrombocytosis is a clonal myeloproliferative disease originating from stem cells that may be associated with other chronic myeloproliferative diseases, such as chronic myeloid leukemia, polycythemia vera, and primary myelofibrosis (24) . The causes of this disease in animals have not been determined.…”
Section: Discussionmentioning
confidence: 99%
“…Additionally, false thrombocytosis may occur associated with the presence of cytoplasmic fragments of nucleated cells and erythrocytes, lipemia, bacteria, or cryoglobulins (10) . In humans, primary or essential thrombocytosis is a clonal myeloproliferative disease originating from stem cells that may be associated with other chronic myeloproliferative diseases, such as chronic myeloid leukemia, polycythemia vera, and primary myelofibrosis (24) . The causes of this disease in animals have not been determined.…”
Section: Discussionmentioning
confidence: 99%
“…Humoral factors are believed to be responsible for the increase in platelets in these patients (23). Studies have demonstrated a quantitative and qualitative abnormal production of platelets originating from abnormal megakaryocytic clones (24).…”
Section: Discussionmentioning
confidence: 99%
“…A TE também denominada trombocitemia idiopática, trombofilia essencial ou trombocitose essencial, é caracterizada pela proliferação exagerada de megacariócitos na medula óssea, levando ao aumento persistente de plaquetas circulantes. Além do número elevado de plaquetas (>600 x 10 9 /L), essa doença é caracterizada pela esplenomegalia importante e um curso clínico de episódios trombóticos e ou hemorrágicos (Leite et al, 2001).…”
Section: Trombocitemia Essencialunclassified
“…Quanto ao prognóstico, a TE tem um curso menos agressivo quando comparado às outras Neoplasias mieloproliferativas, isto devido à sua baixa transformação leucêmica (<2%) nos casos não tratados (Leite et al, 2001).…”
Section: Trombocitemia Essencialunclassified