2007
DOI: 10.1590/s1516-635x2007000400008
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Abstract: Avian Metapneumovirus (aMPV), also called Turkey Rhinotracheitis Virus (TRTV), is an upper respiratory tract infection of turkeys, chickens and other avian species. Five monoclonal antibodies (MAbs) were created against the Brazilian isolate (SHS-BR-121) of aMPV, MAbs 1A5B8; 1C1C4; 2C2E9 and 2A4C3 of IgG1 and MAb 1C1F8 of IgG2a. Four Mabs (1A5B8; 1C1C4; 2C2E9 and 2A4C3) showed neutralizing activity and three (1A5B8; 1C1C4 and 2A4C3) inhibited cellular fusion in vitro. These MAbs were used to investigate antige… Show more

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“…aMPV subtype C was isolated from SPF laying turkey hens with experimentally contaminated eggs up to post-infection (PI) for 7 days [12]; however, Ganapathy et al [13] indicate that the vertical pathway may be short-lived and can play minor role in aMPV transmission.…”
Section: Introductionmentioning
confidence: 99%
“…aMPV subtype C was isolated from SPF laying turkey hens with experimentally contaminated eggs up to post-infection (PI) for 7 days [12]; however, Ganapathy et al [13] indicate that the vertical pathway may be short-lived and can play minor role in aMPV transmission.…”
Section: Introductionmentioning
confidence: 99%