Effects of prebiotics and probiotics on the colonization and immune response of broiler chickens challenged with Salmonella Enteritidis

Abstract

The present study aimed at evaluating the effect of the prebiotic Bio Mos™ (2 kg/ton up to 10 days; 1 kg/ton from 10 to 21 days; and 0.5 kg/ton from 21 days to slaughter), of the probiotic Lac XCL 5x™ (by spray-mixing), of a combination of the two supplements (prebiotic + probiotic), and of one growth promoter antimicrobial agent (Avilamycin at 15 ppm). Birds were orally challenged with inoculated Salmonella Enteritidis (SE) 10(6) CFU at 3 days of age. Four hundred and eighty male Ross chicks were used. The experiment lasted 28 days, and the analyses were conducted at 15 and 28 days of age. Cecum and liver bacterial colonization of production of anti-SE antibiodies, intestinal micrometry and bird performance were assessed. Neither the prebiotic, nor the probiotic influenced performance or production of anti-SE antibodies in SE-challenged birds. Intestinal micrometry and bird mortality were not influenced by prebiotic or probiotic supplementation, or by the antimicrobial agent. The use of an antimicrobial agent produced higher SE CFUs in cecum bacterial counts, while prebiotic and probiotic yielded lower counts. The combination prebiotic+probiotic did not produce significantly different results from the individual use of the additives

Effects of organic acid supplementation on antioxidant capacity and immune responses of broilers challenged orally with <i>Salmonella enterica</i> subsp. <i>enterica Typhimurium</i>

“…Salmonella Typhimurium is an enteric bacterium that can colonize chickens, and is a serovar that is known to cause salmonellosis in broiler chickens (Ribeiro et al, 2007;Van Immerseel et al, 2009). Growth performance parameters in broilers may be regarded as indication of the severity of S. Typhimurium infection.…”

The Effect of Fermented Wheat Germ Extract on Biochemical, Physiological and Performance Parameters of Broiler Chickens

“…Salmonellas in the intestines modulating gut microbiota. Prebiotics are nondigestible carbohydrates containing feed ingredient a substrate for multiplication of useful bacteria in microbiota, prevent or at least suppress colonization of pathogen microflora including Salmonellas (Ribeiro et al, 2007). FWGE is a prebiotic reproductive part of grain kernels that concentrates high protein essential vitamins and minerals, such as potassium, iron, zinc, D, E and B vitamins, and essential fatty acid.…”

Effect of Two Strains of Probiotics on the Antioxidant Capacity, Oxidative Stress, and Immune Responses of Salmonella-Challenged Broilers

“…Ribeiro et al (2007) found that a probiotic had no effect on the production of anti-Salmonella Enteritidis antibodies in Salmonella-challenged birds.…”

“…Salmonella enterica serovar Typhimurium (S. typhimurium) is an enteric bacterium that can colonize chickens; it is a common serovar causing salmonellosis in broiler chickens (Ribeiro et al, 2007).…”