2001
DOI: 10.1590/s1516-44462001000600011
|View full text |Cite
|
Sign up to set email alerts
|

Aspectos neuroquímicos: o papel da serotonina no TOC

Abstract: The therapeutic action of selective serotonin (5-HT) reuptake inhibitors (SSRIs) in obsessive-compulsive disorder (OCD) points to the role of 5-HT in this condition. Functional neuroimaging studies showed hyperactivity of the nucleus caudatum in OCD patients, which disappears following treatment with either SSRIs or cognitive behavior therapy. Pharmacological results indicate hypersensitivity of the 5-HT1D receptor subtype in OCD, similarly reversed by chronic administration of SSRIs. … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
0
0
1

Year Published

2006
2006
2009
2009

Publication Types

Select...
2
1

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
(1 citation statement)
references
References 7 publications
0
0
0
1
Order By: Relevance
“…A observação de que pacientes com TOC respondiam a medicamentos que atuam principalmente no sistema serotoninérgico, levou à hipótese de que este sistema tenha um papel importante na fisiopatologia deste transtorno (Graeff, 2001).…”
Section: Tratamento Farmacológico Do Tocunclassified
“…A observação de que pacientes com TOC respondiam a medicamentos que atuam principalmente no sistema serotoninérgico, levou à hipótese de que este sistema tenha um papel importante na fisiopatologia deste transtorno (Graeff, 2001).…”
Section: Tratamento Farmacológico Do Tocunclassified