IGF-I e IgG séricos e nas secreções lácteas em vacas tratadas com rbST no período pré-parto

Pauletti, Patrícia Mendonça; Bagaldo, Adriana Regina; Kindlein, Líris; Paz, Cláudia Cristina Paro de; Lanna, Dante Pazzanese Duarte; Neto, Raul Machado

doi:10.1590/s1516-35982005000300031

Cited by 9 publications

(11 citation statements)

References 49 publications

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“…The IgG concentration in BC and OC were also measured by RID, described by Mancini et al (1965), and modified by Besser et al (1985). The average IgG concentration determined in the bovine and ovine first milking colostrum were 115.68 6 20.49 mg/ml and 48.13 6 4.98 mg/ml, respectively, similar levels of concentration were found by Pauletti et al (2005) and Loste et al (2008), respectively. These concentrations obtained in the pools represent the average of IgG obtained in a normal commercial operation.…”

Section: Methodsmentioning

confidence: 62%

IgG absorption by Santa Ines lambs fed Holstein bovine colostrum or Santa Ines ovine colostrum

Moretti

Kindlein

Pauletti

et al. 2010

Animal

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The objective of this study was to evaluate the immunoglobulin G (IgG) absorption by Santa Ines lambs under two colostrum management systems usually used by producers. Twenty-seven Santa Ines newborn lambs received two meals of 250 ml of bovine colostrum from Holstein cows (BC group) or ovine colostrum from Santa Ines ewes (OC group) at 0 and 6 h of life. Pools of BC and OC were analyzed by radial immunodiffusion to quantify IgG. Results are expressed as least-square means and standard errors of mean (means 6 s.e.m.). The concentration of IgG in bovine and ovine pools averaged 115.7 6 20.5 and 48.1 6 5.0 mg/ml, respectively, levels of concentration found in similar regular colostrum managements. The efficiency of IgG absorption was evaluated under two aspects, maximum apparent efficiency of absorption and total apparent efficiency of absorption (AEAmax and AEAtotal, respectively). The AEAmax was calculated taking into account the mass of IgG ingested just in the first meal of colostrum at birth and the serum IgG concentration at 6 h while the AEAtotal took into account the serum IgG concentration at 24 h of life that reflects the first colostrum offered at birth and the second meal at 6 h. The IgG and apparent efficiency of absorption results were transformed into the square root and log base 10, respectively, and were presented as geometric leastsquare means. In BC, lower ( P , 0.05) AEAmax and AEAtotal were verified (14.2% and 15.6%, respectively), in relation to OC (23.6% and 24.4%, respectively). Serum IgG concentrations at 24 h were significantly higher ( P , 0.05) in BC (31.4 mg/ml, respectively) compared with OC (22.2 mg/ml, respectively). The results in this study confirm that there is a limitation to the process of IgG absorption by the enterocytes of newborn lambs, which determined a nonlinear behavior of passive immunity acquisition. Similar values of AEAmax and AEAtotal for the two sources of colostrum reveal that the process of IgG absorption from the first and second meals during the first 6 h of life did not change and indicates that the ingestion of a second feeding of quality colostrum can enhance the acquisition of immune protection of newborn lambs.

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Section: Methodsmentioning

confidence: 62%

IgG absorption by Santa Ines lambs fed Holstein bovine colostrum or Santa Ines ovine colostrum

Moretti

Kindlein

Pauletti

et al. 2010

Animal

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“…High concentrations of IGF‐I in bovine colostrum between 200 and 500 ng/mL have been reported, whereas normal milk contains 1–2 ng/mL, increasing to 20–30 ng/mL by the end of the lactation (Vega et al . 1991; Pauletti et al . 2005).…”

Section: Introductionmentioning

confidence: 99%

Insulin‐like growth factor‐I, passive immunity transfer, and stereological characteristics of small intestine of newborn calves

Pauletti

Bagaldo

Kindlein

et al. 2007

Animal Science Journal

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This study evaluated the concentration of insulin‐like growth factor (IGF)‐I present in the mammary secretions, its relation with changes in serum IGF‐I and immunoglobulin (Ig)G, and intestinal mucosa alterations of 42 calves during the first week of life. Cows were randomly assigned to two groups, treated and control, with 21 animals in each. The treated group was injected with 500 mg recombinant bovine somatotropin (rbST) at day −35 relative to predicted calving date. Newborn calves were randomly assigned to a 2 × 3 factorial scheme: dams group and slaughter date (at birth, 2 and 7 days of life). IGF‐I concentration was higher in the colostrum of treated cows (P < 0.05), but did not differ in the subsequent mammary secretions. Immunoglobulin G concentration in colostrum and subsequent mammary secretions did not differ between groups (P > 0.05). No differences were found in calf serum IGF‐I levels from birth to the seventh day or serum immunoglobulin G concentration after 24 h of life (P > 0.05). IGF‐I colostrum levels observed in this study did not affect the small intestine morphometry. The segment from the middle jejunum showed higher mucosa partial volume (Vv) at birth and 7 days old compared to other segments, and at just 2 days of age this segment reduced its Vv, not differing from other segments of the same date.

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“…As variáveis proteína total e imunoglobulinas séricas foram correlacionadas, com valor de r = 0,76, para o período experimental total. Em bovinos, também ocorre elevada correlação entre proteína total e imunoglobulinas Tabela 2 -Composição da ração total consumida pelos cabritos do nascimento até o desaleitamento (%MN) (Nocek et al, 1984;Machado Neto & Packer, 1986;Baracat et al, 1997;Pauletti et al, 2002;Pauletti et al, 2005;Kindlein, 2007). Essa interdependência significativa constitui-se importante indicador de coerência metodológica e fisiológica, uma vez que as variáveis foram analisadas por diferentes métodos analíticos e que 20 a 40% da proteína total é constituída de imunoglobulinas.…”

Section: Resultsunclassified

“…Fleenor & Stott (1980) classificaram colostro bovino com concentrações abaixo de 21,8 mg de imunoglobulinas/mL como de baixo valor imunológico e acima de 49,82 mg/mL como de adequado valor imunológico. Na literatura os valores encontrados para bovinos da raça Holandesa variam de 50 e 120 mg/mL (Burton et al, 1989;Pritchett et al, 1991;Baracat et al, 1997;Tyler et al, 1999;Blum & Hammon, 2000;Morin et al, 2001;Pauletti et al, 2005). Os valores observados neste trabalho para o colostro caprino se encontram dentro dos limites observados para espécie caprina que variam entre 69,3 a 217,8 mg/mL (Santos et al, 1994).…”

Section: Resultsunclassified

Flutuação das variáveis séricas em cabras e estudo comparativo da absorção de anticorpos em cabritos recém-nascidos utilizando colostro bovino e caprino

et al. 2009

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RESUMO -Objetivou-se determinar a flutuação no nível de anticorpos séricos em cabras nos períodos pré e pós-parto e a eficiência do processo de aquisição de imunidade passiva em cabritos recém-nascidos utilizando colostros bovino e caprino, visando à avaliação de uma alternativa de manejo de colostro. Foram utilizadas 18 cabras e suas respectivas crias, num total de 33 animais. A coleta de sangue das cabras foi iniciada 45 dias antes da data prevista para o parto e foi realizada em intervalos de cinco dias até o 5 o dia após o parto. Os cabritos foram distribuídos em dois grupos: um grupo recebeu colostro caprino e o outro colostro bovino. As coletas de sangue foram feitas às 0, 12, 24 e 48 horas e aos 5, 10, 15, 17, 20, 25, 30, 35, 40, 50 e 60 dias de vida. Foram analisadas as concentrações séricas de proteína total e imunoglobulinas, além da concentração de imunoglobinas no colostro. O delineamento experimental foi o inteiramente casualizado e as variáveis séricas analisadas como medidas repetidas. A ausência de queda na concentração sérica de proteínas totais e imunoglobinas no período pré-parto indica que a mobilização de anticorpos para glândula mamária ocorre em concentrações que permitem o animal manter essas variáveis sem grandes alterações. No grupo que recebeu colostro bovino, a data de concentração máxima de proteínas totais (7,16 ± 0,28 g/dL)foi verificada às 48,68 ± 0,70 horas de vida e a de imunoglobinas, às 48,75 ± 0,73 horas, com média de 37,56 ± 2,38 unidades ZST (turvação por sulfato de zinco). No grupo que recebeu colostro caprino, os valores máximos de proteínas totais e imunoglobinas séricas ocorreram mais tardiamente, aos 20,05 ± 1,36 e 20,11 ± 1,72 dias de vida, com médias de 5,91 ± 0,22 g/dL e 28,17 ± 2,05 unidades ZST, respectivamente. O colostro caprino pode ser substituído pelo colostro bovino, que promove melhor aquisição inicial de imunoglobulinas aos neonatos.Palavras-chave: imunoglobulinas, pequenos ruminantes, proteína sérica, Saanen Fluctuation of serum variables in goats and comparative study of antibody absorption in new-born kids using cattle and goat colostrumABSTRACT -The objective of this study was to determine the fluctuation of serum antibodies in goats in the period before and immediately after kidding and the passive immunity acquisition efficiency in kids fed bovine and goat colostrum, to assess an alternative for colostrum management. Eighteen goats and their offspring were used in a total of 33 animals. Goat blood samples started to be collected 45 days before the predicated kidding date, at five-day intervals until the 5 th day post kidding. The kids were distributed in two groups: one group received goat colostrum and the other cattle colostrums. Blood collections were made 0, 12, 24 and 48 hours, and at 5, 10, 15, 17, 20, 25, 30, 40, 50 and 60 days of age. The serum concentration of total protein (TP) and immunoglobulins (Ig), and the colostrum IgG concentration were analyzed. A randomized complete design was used and the serum variables were analyzed as repea...

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IGF-I e IgG séricos e nas secreções lácteas em vacas tratadas com rbST no período pré-parto

Cited by 9 publications

References 49 publications

IgG absorption by Santa Ines lambs fed Holstein bovine colostrum or Santa Ines ovine colostrum

IgG absorption by Santa Ines lambs fed Holstein bovine colostrum or Santa Ines ovine colostrum

Insulin‐like growth factor‐I, passive immunity transfer, and stereological characteristics of small intestine of newborn calves

Flutuação das variáveis séricas em cabras e estudo comparativo da absorção de anticorpos em cabritos recém-nascidos utilizando colostro bovino e caprino

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