2003
DOI: 10.1590/s1516-31802003000300002
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Abstract: CONTEXT:The most frequently used methods for detecting antibodies are the indirect immunofluorescence test and the enzymatic immunoassay (ELISA). The polymerase chain reaction is a molecular biology technique in which the production of large amounts of specific DNA fragments is induced from very low concentrations of complex substrates aloowing the detection of very low amounts of viral particles. OBJECTIVE:To assess the accuracy of serological/ ELISA tests in comparison with the polymerase chain reaction in m… Show more

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Cited by 7 publications
(5 citation statements)
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“…IgM antibodies can also persist for a long time after infection in some healthy individuals [9]. Similarly to our result Parmigiani et al [10] reported that the accuracy of the serological tests for the diagnosis of CMV infection was lower than that of the polymerase chain reaction. Also in agreement with our data, Shams and his colleagues (2011) concluded that PCR was a more sensitive, reliable and accurate method for the detection of CMV infection in pregnant women.…”
Section: Discussionsupporting
confidence: 89%
“…IgM antibodies can also persist for a long time after infection in some healthy individuals [9]. Similarly to our result Parmigiani et al [10] reported that the accuracy of the serological tests for the diagnosis of CMV infection was lower than that of the polymerase chain reaction. Also in agreement with our data, Shams and his colleagues (2011) concluded that PCR was a more sensitive, reliable and accurate method for the detection of CMV infection in pregnant women.…”
Section: Discussionsupporting
confidence: 89%
“…The rate of infection by CMV among women attending the antenatal clinics was found to be high (95%) but similar to the results of studies performed in Egypt and Brazil (96% and 98% respectively). Similar studies done in India, Japan and Belgrade revealed lower seroprevalences (87.4, 45% and 21.4%) [6][7][8][9][10] . The high seroprevalence of CMV infection among the studied group may be due to poor socioeconomic conditions and hygienic practices known to play a role in the transmission of the virus.…”
Section: Discussionsupporting
confidence: 64%
“…6 Parmigiani et al reported that the accuracy of the serological tests for the diagnosis of CMV infection was lower than that of the polymerase chain reaction. 6,22 Seropevalence of CMV IgG in all age groups was generally high. 100% seropostivity for CMV IgG was also seen in each age groups 11-20 and 21-30 years.…”
Section: Discussionmentioning
confidence: 97%