Development and characterization of a novel bioresorbable and bioactive biomaterial based on polyvinyl acetate, calcium carbonate and coralline hydroxyapatite

Abstract

Coralina® HAP-200 (coralline hydroxyapatite obtained by hydrothermal treatment of marine corals) and POVIAC ® (polymeric matrix based on PVAc), commercial trade marks were mixed with a natural product from the Cuban sea costs, i.e. calcium carbonate from Porites Porites coral, to obtain a novel bioactive composite with potential use as bone restoration material. The samples were characterized by physical-chemical (FTIR, XRD, SEM, EDS) and mechanical studies. It was shown that there is no chemical interaction between the inorganic filler and the polymer matrix, each conserving the original properties of the raw materials. The studied formulation had a compressive strength similar to that reported for trabecular bone. Scanning electron microscopy examination revealed that the addition of CaCO 3 induces a change on the morphologic structure of the composite obtained after 30 days of SBF immersion. These composites generate novel biomaterials capable of promoting the deposition of a new phase, a Ca-P layer due to the bioactivity of a Ca 2+ precursors.

Anticorrosive coating based on poly(vinyl acetate) formed by electropolymerization on the copper surface

“…It is readily accepted by the human body and used in biomedical applications. In admixture with poly(vinyl alcohol), PVAC is used as a matrix for controlled release of drugs …”

Compression Performance and Deformation Behavior of 3D-Printed PLA-Based Lattice Structures

“…More characteristic peaks of inorganic fillers were also observed. For example, strong pea CaCO3 at 29.5°, 35.9°, and 39.4°were detected in composite filaments [25], confirmin successful incorporation of CaCO3. The effect of the addition of CaCO3 and TCP on the tensile behavior of the comp filament is presented in Figure 4.…”

“…Moreover, characteristic peaks of inorganic fillers were also observed. For example, strong peaks of CaCO 3 at 29.5 • , 35.9 • , and 39.4 • were detected in composite filaments [25], confirming the successful incorporation of CaCO 3 .…”

Fabrication of Bone Scaffolds from Cockle Shell Waste

“…The scaffold serves as a temporary template for bone cell attachment and regeneration where at the same time it gradually degrades to allow new bone tissue to form. An ideal scaffold must meet several requirements such as biocompatibility [7,8], bioresorbability [8,9], good mechanical characteristics [7,10], biodegradability [9], high interconnected porosity [8], and ability to promote cell activities [8,11] such as cell adhesion, proliferation, migration, and differentiation. At the same time, it is a real challenge to obtain an excellent scaffold due to many factors that affect the scaffold properties.…”